Acne vulgaris is a common disease that carries an enormous financial and psychosocial
impact. Androgens, excessive sebum production, ductal hypercornification, changes in the …

In recent years, significant progress has been made in the understanding of the
pathophysiological mechanisms of acne and the role of Propionibacterium acnes. With this …

A microbial aetiology of acne has been suggested since the beginning of the last century.
There is considerable evidence, circumstantial at best, which suggests that micro …

We have come a long way since 1896, when it was first suggested that Propionibacterium
acnes, found in acne lesions, was the cause of acne. Although several lines of evidence …

Acne is a common disease that in cases of extreme disfiguration can have severe
consequences for the personality development of young people and is associated with a …

While the commensal bacterium Propionibacterium acnes (P. acnes) is involved in the
maintenance of a healthy skin, it can also act as an opportunistic pathogen in acne vulgaris …

The inflammatory stage of acne vulgaris is usually of greatest concern to the patient. A
number of morphologically different inflammatory lesions may form that can be painful and …

Background The pathogenesis of acne vulgaris is multifactorial with increased sebum
production, alteration in the quality of sebum lipids, dysregulation of the hormone …

The conventional perspective of acne pathogenesis holds that Propionibacterium acnes
colonizes the duct of the sebaceous follicle, causing an innate immune response and the …

Acne is a chronic inflammatory disease of the sebaceous-pilosebaceous unit. Interestingly,
inflammation can be detected by histopathological examination and immuohistochemical …