Calcium-related damage in ischemia
T Kristián, BK Siesjö - Life sciences, 1996 - Elsevier
The objective of this hypothesis article is to review evidence supporting a role for calcium in
mediating ischemic brain damage, and to present data which puts mitochondrial dysfunction …
mediating ischemic brain damage, and to present data which puts mitochondrial dysfunction …
Calcium and ischemic brain damage
BK Siesjö - European Neurology, 1986 - karger.com
An account is given of calcium metabolism in the brain, with particular reference to the
possibility that loss of calcium homeostasis is the cause of ischemic neuronal necrosis. The …
possibility that loss of calcium homeostasis is the cause of ischemic neuronal necrosis. The …
Mitochondrial calcium sequestration in cortical and hippocampal neurons after prolonged ischemia of the cat brain
KA Hossmann, BG Ophoff, R Schmidt-Kastner… - Acta …, 1985 - Springer
Adult normothermic cats were submitted to 1-h complete cerebrocirculatory arrest, followed
by blood recirculation for 6–8 h. Two groups of animals could be distinguished: In one group …
by blood recirculation for 6–8 h. Two groups of animals could be distinguished: In one group …
Mitochondrial calcium and oxidative stress as mediators of ischemic brain injury
AA Starkov, C Chinopoulos, G Fiskum - Cell calcium, 2004 - Elsevier
Acute ischemic and brain injury is triggered by excitotoxic elevation of intraneuronal Ca2+
followed by reoxygenation-dependent oxidative stress, metabolic failure, and cell death …
followed by reoxygenation-dependent oxidative stress, metabolic failure, and cell death …
Disturbances of calcium homeostasis within the endoplasmic reticulum may contribute to the development of ischemic-cell damage
W Paschen - Medical hypotheses, 1996 - Elsevier
It is widely accepted that disturbances of calcium homeostasis play a key role in the
development of cell damage produced by transient cerebral ischemia. It is believed that the …
development of cell damage produced by transient cerebral ischemia. It is believed that the …
The role of calcium in ischemic myocardial injury.
JG Murphy, JD Marsh, TW Smith - Circulation, 1987 - europepmc.org
Hypoxia and ischemia produce depression of myocardial contractile function and alterations
in calcium homeostasis. Although both functional abnormalities and alterations in calcium …
in calcium homeostasis. Although both functional abnormalities and alterations in calcium …
A role for the mitochondrion in the protection of cells against calcium overload?
DG Nicholls - Progress in brain research, 1985 - Elsevier
Publisher Summary This chapter describes the pathways that are responsible for
mitochondrial calcium transport and discusses these pathways that act in concert to limit the …
mitochondrial calcium transport and discusses these pathways that act in concert to limit the …
Calcium in the mitochondria following brief ischemia of gerbil brain
E Dux, G Mies, KA Hossmann, L Siklós - Neuroscience letters, 1987 - Elsevier
Calcium was localized in neurons and glial cells of the CA 1 region of hippocampus and in
neurons of parietal cortex with the oxalate-pyroantimonate electron cytochemical method …
neurons of parietal cortex with the oxalate-pyroantimonate electron cytochemical method …
[PDF][PDF] Mitochondrial calcium handling and oxidative stress
AP Halestrap, EJ Griffiths… - Biochemical Society …, 1993 - researchgate.net
Tissues subjected to chemical poisoning or ischaemia followed by reperfusion experience
oxidative stress as a result of both an increase in oxygen free radical species and a …
oxidative stress as a result of both an increase in oxygen free radical species and a …
Role of calcium in neuronal cell injury: which subcellular compartment is involved?
W Paschen - Brain research bulletin, 2000 - Elsevier
It is widely believed that calcium plays a primary role in the development of neuronal cell
injury in different pathological states of the brain. Disturbances of calcium homeostasis may …
injury in different pathological states of the brain. Disturbances of calcium homeostasis may …