DNA methylation is a major epigenetic modification of vertebrate genomes that is mostly
associated with transcriptional repression. During embryogenesis, DNA methylation …

DNA methylation is globally reprogrammed during mammalian preimplantation
development, which is critical for normal development. Recent reduced representation …

Vertebrate genomes are marked by notably high levels of 5-cytosine DNA methylation
(5meC). The clearest function of DNA methylation among members of the subphylum is …

ABSTRACT DNA methylation is a highly conserved epigenetic modification that plays
essential roles in mammalian gene regulation, genome stability and development. Despite …

DNA methylation is a fundamentally important epigenetic modification of the mammalian
genome that has widespread influences on gene expression. During germ-cell specification …

While DNA cytosine methylation is relatively stable in somatic tissues, it is highly dynamic
during preimplantation development. A recent study in Nature by Meissner and colleagues …

In mammals, DNA methylation is a crucial epigenetic modification with key functions during
development. Cellular processes that are regulated by DNA methylation comprise X …

DNA methylation plays important roles during development. However, the DNA methylation
reprogramming of functional elements has not been fully investigated during mammalian …

Background Uncovering mechanisms of epigenome evolution is an essential step towards
understanding the evolution of different cellular phenotypes. While studies have confirmed …

Epigenetics refers to heritable phenotypic alterations in the absence of DNA sequence
changes, and DNA methylation is one of the extensively studied epigenetic alterations. DNA …