The hippocampus is a key brain region regulating complex cognitive and emotional
responses, and is implicated in the etiology of depressive and anxiety disorders, many of …

Background Oestradiol is a steroid hormone that exerts extensive influence on brain
development and is a powerful modulator of hippocampal structure and function. The …

Sex differences exist in the regulation of adult neurogenesis in the hippocampus in
response to hormones and cognitive training. Here, we investigated the trajectory and …

Gonadal hormones modulate neurogenesis in the dentate gyrus differentially in male and
female adult rodents. Neurogenesis is comprised of at least two components: cell …

To determine whether a sex difference exists in the production of hippocampal cells during
adulthood, we examined proliferating cells and their progeny in adult rats using the …

Sex differences in the function of the hippocampus have been observed in numerous
mammalian species. However, the magnitude, extent, and specificity of these differences are …

Androgens (testosterone and DHT) increase adult hippocampal neurogenesis by increasing
survival of new neurons in male rats and mice via an androgen receptor pathway, but it is …

Numerous studies provide increasing evidence, which supports the ideas that every cell in
the brain of males may differ from those in females due to differences in sex chromosome …

Numerous studies have demonstrated differences between males and females in
hippocampal structure, function, and plasticity. There also are many studies about the …

The hippocampus is an area of the brain that undergoes dramatic plasticity in response to
experience and hormone exposure. The hippocampus retains the ability to produce new …