Objective: We aimed to study if age-related white matter changes (WMC) and vascular risk
factors were predictors of cognitive decline in elderly subjects with WMC living …

Objectives: We compared the ability of molecular biomarkers for Alzheimer disease (AD),
including amyloid imaging and CSF biomarkers (Aβ42, tau, ptau181, tau/Aβ42 …

Introduction Vascular factors increase the risk of Alzheimer's disease (AD). We investigated
the associations between such factors, longitudinal AD cerebrospinal fluid biomarkers, and …

Objectives To assess the relation between socioeconomic status (SES) and structural brain
change in nondemented older adults and to ascertain the potential role of preclinical …

Objective To develop, replicate, and validate an MRI-based quantitative measure of both
cerebrovascular and neurodegeneration in Alzheimer disease (AD) for clinical and …

Recent epidemiological and clinico-pathological data indicate considerable overlap
between cerebrovascular disease (CVD) and Alzheimer's disease (AD) and suggest …

Objective Examine the effects of subcortical infarcts with Alzheimer's disease (AD) pathology
on dementia, episodic memory, and other cognitive abilities in older persons. Methods …

Objective Assess Aβ deposition longitudinally and explore its relationship with cognition and
disease progression. Methods Clinical follow‐up was obtained 20±3 months after [11C] …

Objective: A study was undertaken to examine the relation of Alzheimer disease (AD)
pathology, cerebral infarcts, and Lewy body (LB) pathology to cognition in persons without …

Objective: To test the hypotheses predicted in a hypothetical model of Alzheimer disease
(AD) biomarkers that rates of β-amyloid (Aβ) accumulation on PET imaging are not related to …