Carotid atherosclerosis and cognitive decline in patients with Alzheimer's disease

M Silvestrini, B Gobbi, P Pasqualetti, M Bartolini… - Neurobiology of …, 2009 - Elsevier
Aim of the study was to explore the correlation between the progression of carotid
atherosclerosis and the evolution of cognitive impairment in 66 patients with Alzheimer's …

Vascular risk factors promote conversion from mild cognitive impairment to Alzheimer disease

J Li, YJ Wang, M Zhang, ZQ Xu, CY Gao, CQ Fang… - Neurology, 2011 - AAN Enterprises
Objective: Growing evidence suggests that vascular risk factors (VRF) contribute to cognitive
decline. The aim of this study was to investigate the impact of VRF on the conversion from …

Influence of amyloid-β on cognitive decline after stroke/transient ischemic attack: three-year longitudinal study

W Liu, A Wong, L Au, J Yang, Z Wang, EYL Leung… - Stroke, 2015 - Am Heart Assoc
Background and Purpose—We hypothesized that comorbid amyloid-beta (Aβ) deposition
played a key role in long-term cognitive decline in subjects with stroke/transient ischemic …

Association between elevated brain amyloid and subsequent cognitive decline among cognitively normal persons

MC Donohue, RA Sperling, R Petersen, CK Sun… - Jama, 2017 - jamanetwork.com
Importance Among cognitively normal individuals, elevated brain amyloid (defined by
cerebrospinal fluid assays or positron emission tomography regional summaries) can be …

[HTML][HTML] Cerebral blood flow and amyloid-β interact to affect memory performance in cognitively normal older adults

KJ Bangen, AL Clark, EC Edmonds… - Frontiers in aging …, 2017 - frontiersin.org
Cerebral blood flow (CBF) alterations and amyloid-β (Aβ) accumulation have been
independently linked to cognitive deficits in older adults at risk for dementia. Less is known …

Adverse vascular risk is related to cognitive decline in older adults

AL Jefferson, TJ Hohman, D Liu… - Journal of …, 2015 - content.iospress.com
Background: Cardiovascular disease (CVD) and related risk factors are associated with
Alzheimer's disease (AD). This association is less well-defined in normal cognition (NC) or …

[HTML][HTML] Neuroimaging of cerebral small vessel disease and age-related cognitive changes

MR Caunca, A De Leon-Benedetti, L Latour… - Frontiers in aging …, 2019 - frontiersin.org
Subclinical cerebrovascular disease is frequently identified in neuroimaging studies and is
thought to play a role in the pathogenesis of cognitive disorders. Identifying the etiologies of …

Effect of lifestyle activities on Alzheimer disease biomarkers and cognition

P Vemuri, TG Lesnick, SA Przybelski… - Annals of …, 2012 - Wiley Online Library
Objective: A study was undertaken to investigate the association of intellectual and physical
activity with biomarkers of Alzheimer disease (AD) pathophysiology and cognition in a …

Prevalence and outcomes of vascular cognitive impairment

K Rockwood, C Wentzel, V Hachinski, DB Hogan… - Neurology, 2000 - AAN Enterprises
Objective: To assess the importance of vascular cognitive impairment and its three
subgroups (cognitive impairment, no dementia; vascular dementia; and AD with a vascular …

The metabolic brain signature of cognitive resilience in the 80+: beyond Alzheimer pathologies

EM Arenaza-Urquijo, SA Przybelski, TL Lesnick… - Brain, 2019 - academic.oup.com
Research into cognitive resilience imaging markers may help determine the clinical
significance of Alzheimer's disease pathology among older adults over 80 years (80+). In …