Stem cell therapy has the optimistic goal of regenerating the myocardium as defined by re-
growth of lost or destroyed myocardium. As applied to patients with heart failure, many …

Dramatic evolution in medical and catheter interventions and complex surgeries to treat
children with congenital heart disease (CHD) has led to a growing number of patients with a …

Significant achievements in paediatric cardiology, surgical treatment and intensive care of
congenital heart disease have drastically changed clinical outcomes for paediatric patients …

Heart failure remains the leading cause of death worldwide, and is a burgeoning problem in
public health due to the limited capacity of postnatal hearts to self-renew. The …

Opinion statement As heart transplantation and mechanical assist technology are
inadequate solutions for the growing clinical epidemic of heart failure, myocardial …

Cell therapy as a means to cure ischemic heart disease and end-stage heart failure has
been under investigation for several years. Many clinical studies have been conducted with …

Despite declining mortality from cardiovascular diseases, the prevalence of heart failure
continues to increase and is itself associated with increasing morbidity, mortality and …

Heart failure is one of the leading causes of morbidity and mortality globally. Myocardial
infarction remains one of the primary causes of chronic heart failure due to cardiac …

It has now been almost 20 years since first clinical trials of stem cell therapy for heart repair
were initiated. While initial preclinical data were promising and suggested that stem cells …

Regenerative medicine aims to achieve functional and structural restoration of a failing
organ. Applied to cardiovascular medicine and surgery, this emerging discipline offers a …