Coronary restenotic reduction of drug-eluting stenting may be due to its anti-inflammatory effects

JJ Li, J Li, JL Nan, Z Li, X Zhen, CW Mu, J Dai… - Medical hypotheses, 2007 - Elsevier
The development of coronary stent has revolutionized the field of interventional cardiology
by reducing the incidence of restenosis after balloon angioplasty. However, the stent has still …

Is inflammation a contributor for coronary stent restenosis?

JJ Li, SP Nie, CY Zhang, Z Gao, X Zheng, YL Guo - Medical hypotheses, 2007 - Elsevier
The development of coronary stent has revolutionized the field of interventional cardiology
by reducing the incidence of restenosis after balloon angioplasty. Despite significant …

Inflammation as a mechanism and therapeutic target for in-stent restenosis

DE Drachman, DI Simon - Current Atherosclerosis Reports, 2005 - Springer
Restenosis following coronary stenting has long been attributed to neointimal proliferation,
thrombosis, and negative remodeling. More recently, the important role of inflammation in …

Prevention of restenosis after stenting: the emerging role of inflammation

F Versaci, A Gaspardone - Coronary artery disease, 2004 - journals.lww.com
Restenosis after stent implantation is mainly caused by neointimal proliferation through the
stent struts. Experimental studies indicate a marked activation of inflammatory cells at the …

The late-phase inflammatory response after drug-eluting stent implantation

I Taguchi, S Yoneda, S Abe, S Toyoda, T Nasuno… - Heart and vessels, 2014 - Springer
Recent advances in drug-eluting stent (DES) technology have succeeded in preventing
restenosis. In addition to inhibiting smooth muscle cell proliferation, DES greatly inhibits the …

Coronary stenting and inflammation

A Gaspardone, F Versaci - The American journal of cardiology, 2005 - Elsevier
Restenosis after stent implantation is mainly caused by neointimal proliferation through the
stent struts. Experimental studies performed in the last decade indicate that inflammatory …

Late-phase inflammatory response as a feature of in-stent restenosis after drug-eluting stent implantation

S Yoneda, S Abe, T Kanaya, K Oda… - Coronary artery …, 2013 - journals.lww.com
Objectives The aim of this study was to compare pathological features among in-stent
restenosis lesions after drug-eluting stent (DES) placement, those after bare metal stent …

Antiinflammatory approaches to restenosis

IK De Scheerder, Y Huang - Local Drug Delivery for Coronary …, 2005 - taylorfrancis.com
Restenosis remains a major limitation of coronary angioplasty. A complex
pathophysiological process, restenosis is thought to be the result of an exaggerated healing …

In-stent restenosis: contributions of inflammatory responses and arterial injury to neointimal hyperplasia

R Kornowski, MK Hong, FO Tio, O Bramwell… - Journal of the American …, 1998 - jacc.org
Objectives. We examined the relative contributions of inflammation and arterial injury to
neointimal formation in a porcine coronary overstretch restenosis model. Background …

Editorial (Hot Topics: Inflammation: A Key Mechanism of Adverse Reactions to Coronary Stent and A Target for Future Therapies)

G Niccoli - Current Vascular Pharmacology, 2013 - ingentaconnect.com
Treatment of coronary artery disease has been increasingly performed by coronary stenting
in recent years. The introduction of bare metal stent (BMS) was felt as an advancement …