Despite extensive research on astrocytic Ca2+ in synaptic transmission, its contribution to
the modulation of sensory transmission during different brain states remains largely …

Neural activity is diverse, and varies depending on brain regions and sleep/wakefulness
states. However, whether astrocyte activity differs between sleep/wakefulness states, and …

Astrocytic Ca2+ signaling has been intensively studied in health and disease but has not
been quantified during natural sleep. Here, we employ an activity-based algorithm to assess …

Mammalian sleep expression and regulation have historically been thought to reflect the
activity of neurons. Changes in other brain cells (glia) across the sleep-wake cycle and their …

Rapid eye movement (REM) sleep onset is triggered by disinhibition of cholinergic neurons
in the pons. During REM sleep, the brain exhibits prominent activity in the 5–8 Hz (theta) …

The role of astrocytes in neuronal function has received increasing recognition, but
disagreement remains about their function at the circuit level. Here we use in vivo two …

Monitoring astrocytic Ca2+ activity is essential to understand the physiological and
pathological roles of astrocytes in the brain. However, previous commonly used methods for …

The integration of external information with the internal state of the body is central to the
survival of virtually every multicellular organism. However, a complete picture of the …

Elevation of intracellular Ca2+ in astrocytes can influence cerebral microcirculation and
modulate synaptic transmission. Recently, in vivo imaging studies identified delayed …

Astrocytes are a direct target of neuromodulators and can influence neuronal activity on
broad spatial and temporal scales in response to a rise in cytosolic calcium. However, our …