Distinct astrocytic modulatory roles in sensory transmission during sleep, wakefulness, and arousal states in freely moving mice
Despite extensive research on astrocytic Ca2+ in synaptic transmission, its contribution to
the modulation of sensory transmission during different brain states remains largely …
the modulation of sensory transmission during different brain states remains largely …
Region-specific and state-dependent astrocyte Ca2+ dynamics during the sleep-wake cycle in mice
T Tsunematsu, S Sakata, T Sanagi… - Journal of …, 2021 - Soc Neuroscience
Neural activity is diverse, and varies depending on brain regions and sleep/wakefulness
states. However, whether astrocyte activity differs between sleep/wakefulness states, and …
states. However, whether astrocyte activity differs between sleep/wakefulness states, and …
Astrocytic Ca2+ signaling is reduced during sleep and is involved in the regulation of slow wave sleep
Astrocytic Ca2+ signaling has been intensively studied in health and disease but has not
been quantified during natural sleep. Here, we employ an activity-based algorithm to assess …
been quantified during natural sleep. Here, we employ an activity-based algorithm to assess …
[HTML][HTML] A role for astroglial calcium in mammalian sleep and sleep regulation
AM Ingiosi, CR Hayworth, DO Harvey, KG Singletary… - Current Biology, 2020 - cell.com
Mammalian sleep expression and regulation have historically been thought to reflect the
activity of neurons. Changes in other brain cells (glia) across the sleep-wake cycle and their …
activity of neurons. Changes in other brain cells (glia) across the sleep-wake cycle and their …
Astrocytic IP3/Ca2+ Signaling Modulates Theta Rhythm and REM Sleep
J Foley, T Blutstein, SY Lee, C Erneux… - Frontiers in neural …, 2017 - frontiersin.org
Rapid eye movement (REM) sleep onset is triggered by disinhibition of cholinergic neurons
in the pons. During REM sleep, the brain exhibits prominent activity in the 5–8 Hz (theta) …
in the pons. During REM sleep, the brain exhibits prominent activity in the 5–8 Hz (theta) …
Astrocytes regulate cortical state switching in vivo
KE Poskanzer, R Yuste - Proceedings of the National …, 2016 - National Acad Sciences
The role of astrocytes in neuronal function has received increasing recognition, but
disagreement remains about their function at the circuit level. Here we use in vivo two …
disagreement remains about their function at the circuit level. Here we use in vivo two …
Monitoring Astrocytic Ca2+ Activity in Freely Behaving Mice
H Qin, W He, C Yang, J Li, T Jian, S Liang… - Frontiers in Cellular …, 2020 - frontiersin.org
Monitoring astrocytic Ca2+ activity is essential to understand the physiological and
pathological roles of astrocytes in the brain. However, previous commonly used methods for …
pathological roles of astrocytes in the brain. However, previous commonly used methods for …
Astrocytes: integrators of arousal state and sensory context
The integration of external information with the internal state of the body is central to the
survival of virtually every multicellular organism. However, a complete picture of the …
survival of virtually every multicellular organism. However, a complete picture of the …
Rapid astrocyte calcium signals correlate with neuronal activity and onset of the hemodynamic response in vivo
IR Winship, N Plaa, TH Murphy - Journal of Neuroscience, 2007 - Soc Neuroscience
Elevation of intracellular Ca2+ in astrocytes can influence cerebral microcirculation and
modulate synaptic transmission. Recently, in vivo imaging studies identified delayed …
modulate synaptic transmission. Recently, in vivo imaging studies identified delayed …
Multicore fiber optic imaging reveals that astrocyte calcium activity in the mouse cerebral cortex is modulated by internal motivational state
Astrocytes are a direct target of neuromodulators and can influence neuronal activity on
broad spatial and temporal scales in response to a rise in cytosolic calcium. However, our …
broad spatial and temporal scales in response to a rise in cytosolic calcium. However, our …