Daidzein attenuates inflammation and exhibits antifibrotic effect against Bleomycin-induced pulmonary fibrosis in Wistar rats

S Soumyakrishnan, G Sudhandiran - Biomedicine & Preventive Nutrition, 2011 - Elsevier
Among the acute and chronic lung diseases, pulmonary fibrosis (PF) is the most fatal one
because of its prognosis and treatment is so far an unsuccessful task. In this study, we have …

Sodium houttuyfonate inhibits bleomycin induced pulmonary fibrosis in mice

Y Shen, M Cheng, X Liu, D Zhu, J Gao - Frontiers in Pharmacology, 2021 - frontiersin.org
Pulmonary fibrosis (PF) could severely disrupt the normal lung architecture and function with
fatal consequences. Currently, there is no effective treatment for PF or idiopathic pulmonary …

Glycyrrhizic acid alleviates bleomycin-induced pulmonary fibrosis in rats

L Gao, H Tang, H He, J Liu, J Mao, H Ji… - Frontiers in …, 2015 - frontiersin.org
Idiopathic pulmonary fibrosis is a progressive and lethal form of interstitial lung disease that
lacks effective therapies at present. Glycyrrhizic acid (GA), a natural compound extracted …

[HTML][HTML] Regulatory effect of caffeic acid phenethyl ester on type I collagen and interferon-gamma in bleomycin-induced pulmonary fibrosis in rat

A Larki, AA Hemmati, A Arzi… - Research in …, 2013 - ncbi.nlm.nih.gov
Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease of unknown etiology. Recent
investigations have demonstrated that the impaired immune response is a common …

Inula japonica ameliorated bleomycin-induced pulmonary fibrosis via inhibiting soluble epoxide hydrolase

WY Zhao, ZL Luan, TT Liu, WH Ming, XK Huo… - Bioorganic …, 2020 - Elsevier
Pulmonary fibrosis is a progressive, irreversible, and fatal fibrotic lung disease with a high
mortality and morbidity, and commonly nonresponsive to conventional therapy. Inula …

A standardized herbal extract PM014 ameliorates pulmonary fibrosis by suppressing the TGF-β1 pathway

KH Kim, S Lee, H Lee, D Shin, D Min, M Kim, B Ryu… - Scientific reports, 2018 - nature.com
Idiopathic pulmonary fibrosis (IPF) is a devastating and common chronic lung disease
pathologically characterized by loss of epithelial cells and activation of fibroblasts and …

Dihydroartemisinin alleviates oxidative stress in bleomycin-induced pulmonary fibrosis

D Yang, J Qiu, HH Zhou, Y Yu, D Zhou, Y Xu, M Zhu… - Life sciences, 2018 - Elsevier
Aims Dihydroartemisinin has been shown to inhibit the development of pulmonary fibrosis in
rats, but its mechanism has yet to be elucidated. This study aimed to determine the …

A Chinese herbal formula ameliorates pulmonary fibrosis by inhibiting oxidative stress via upregulating Nrf2

Y Bai, J Li, P Zhao, Y Li, M Li, S Feng, Y Qin… - Frontiers in …, 2018 - frontiersin.org
This study aimed to explore the protective effects of a Chinese herbal formula, Jinshui
Huanxian formula (JHF), on experimental pulmonary fibrosis and its underlying …

[HTML][HTML] Effects of plant extracts and bioactive compounds on attenuation of bleomycin-induced pulmonary fibrosis

S Hosseini, M Imenshahidi, H Hosseinzadeh… - Biomedicine & …, 2018 - Elsevier
Introduction Bleomycin (BLM) is a chemotherapeutic agent that is used in the management
of some human cancers such as lymphomas and squamous cell carcinomas. The major …

Astragaloside IV improves bleomycin-induced pulmonary fibrosis in rats by attenuating extracellular matrix deposition

LC Li, L Xu, Y Hu, WJ Cui, WH Cui, WC Zhou… - Frontiers in …, 2017 - frontiersin.org
Pulmonary fibrosis is a devastating lung disorder with mysterious pathogenesis and limited
treatment options. It is well-recognized that the uncontrolled proliferation of lung fibroblasts …