[HTML][HTML] Sarcopenia: molecular pathways and potential targets for intervention

J Pascual-Fernández, A Fernández-Montero… - International Journal of …, 2020 - mdpi.com
Aging is associated with sarcopenia. The loss of strength results in decreased muscle mass
and motor function. This process accelerates the progressive muscle deterioration observed …

[HTML][HTML] Sarcopenia–Molecular mechanisms and open questions

P Wiedmer, T Jung, JP Castro, LCD Pomatto… - Ageing research …, 2021 - Elsevier
Sarcopenia represents a muscle-wasting syndrome characterized by progressive and
generalized degenerative loss of skeletal muscle mass, quality, and strength occurring …

[HTML][HTML] Molecular mechanism and pathogenesis of sarcopenia: An overview

A Picca, R Calvani - International journal of molecular sciences, 2021 - mdpi.com
Sarcopenia involves a progressive age-related decline of skeletal muscle mass and
strength/function [1]. This muscle loss is associated with increased risk of adverse health …

[HTML][HTML] Pathophysiology and mechanisms of primary sarcopenia

H Nishikawa, S Fukunishi, A Asai… - International …, 2021 - spandidos-publications.com
Aging causes skeletal muscle atrophy, and myofiber loss can be a critical component of this
process. In 1989, Rosenberg emphasized the importance of the loss of skeletal muscle …

Sarcopenia: age-related skeletal muscle changes from determinants to physical disability

A Di Iorio, M Abate, D Di Renzo… - International journal …, 2006 - journals.sagepub.com
Human aging is characterized by skeletal muscle wasting, a debilitating condition which sets
the susceptibility for diseases that directly affect the quality of life and often limit life span …

[HTML][HTML] Sarcopenia–endocrinological and neurological aspects

MK Stangl, W Böcker, V Chubanov… - Experimental and …, 2019 - thieme-connect.com
Sarcopenia in geriatric patients is often associated with or even caused by changes of the
endocrine and nervous system. The multifactorial pathogenesis of sarcopenia and …

[HTML][HTML] Mechanisms underlying metabolic syndrome-related sarcopenia and possible therapeutic measures

ME Rubio-Ruiz, V Guarner-Lans… - International journal of …, 2019 - mdpi.com
Although there are several reviews that report the interrelationship between sarcopenia and
obesity and insulin resistance, the relation between sarcopenia and the other signs that …

Sarcopenia: assessment of disease burden and strategies to improve outcomes

I Liguori, G Russo, L Aran, G Bulli, F Curcio… - … interventions in aging, 2018 - Taylor & Francis
Life expectancy is increasing worldwide, with a resultant increase in the elderly population.
Aging is characterized by the progressive loss of skeletal muscle mass and strength–a …

[HTML][HTML] Sarcopenia and muscle aging: a brief overview

T Dao, AE Green, YA Kim, SJ Bae, KT Ha… - Endocrinology and …, 2020 - ncbi.nlm.nih.gov
The world is facing the new challenges of an aging population, and understanding the
process of aging has therefore become one of the most important global concerns …

Sarcopenia–The search for emerging biomarkers

A Kalinkovich, G Livshits - Ageing research reviews, 2015 - Elsevier
Sarcopenia, an age-related decline in skeletal muscle mass and function, dramatically
affects the life quality of elder people. In view of increasing life expectancy, sarcopenia …