Inflammatory bowel disease: epidemiology, pathogenesis, and therapeutic opportunities

SB Hanauer - Inflammatory bowel diseases, 2006 - academic.oup.com
Ulcerative colitis (UC) and Crohn's disease (CD), the primary constituents of inflammatory
bowel disease (IBD), are precipitated by a complex interaction of environmental, genetic …

Biologic therapy for inflammatory bowel disease

S Ardizzone, GB Porro - Drugs, 2005 - Springer
Despite all of the advances in our understanding of the pathophysiology of inflammatory
bowel disease (IBD), we still do not know its cause. Some of the most recently available data …

Inflammatory bowel disease: past, present, and future

BE Sands - Journal of gastroenterology, 2007 - Springer
Crohn's disease and ulcerative colitis, collectively known as the inflammatory bowel
diseases (IBD), are largely diseases of the twentieth century, and are associated with the …

Inflammation in the intestinal tract: pathogenesis and treatment

RS Blumberg - Digestive diseases, 2009 - karger.com
Over the past decade a major hypothesis has emerged for the etiopathogenesis of
inflammatory bowel disease (IBD). This hypothesis proposes that IBD represents a …

Inflammatory bowel disease: Established and evolving considerations on its etiopathogenesis and therapy

A Schirbel, C Fiocchi - Journal of digestive diseases, 2010 - Wiley Online Library
Modern studies of inflammatory bowel disease (IBD) pathogenesis have been pursued for
about four decades, a period of time where the pace of progress has been steadily …

Inflammatory bowel disease: progress and current concepts of etiopathogenesis

F Scaldaferri, C Fiocchi - Journal of digestive diseases, 2007 - Wiley Online Library
Over the past few years, none of the numerous conditions that are grouped under the broad
designation of 'chronic inflammatory or autoimmune disorders' has undergone as much …

The immune response in inflammatory bowel disease

SJ Brown, L Mayer - Official journal of the American College of …, 2007 - journals.lww.com
Ulcerative colitis (UC) and Crohn's disease (CD), collectively referred to as inflammatory
bowel disease (IBD), present with differing histologic and cytokine profiles. While the precise …

Prospects for research in inflammatory bowel disease

RS Blumberg, W Strober - Jama, 2001 - jamanetwork.com
Inflammatory bowel disease is a chronic inflammatory condition of the gastrointestinal tract
that manifests as ulcerative colitis and Crohn disease. Both these clinical entities result from …

The pathogenesis of inflammatory bowel disease: translational implications for clinicians

MT Abreu - Current gastroenterology reports, 2002 - Springer
Research in the pathogenesis of inflammatory bowel disease (IBD) has dramatically
broadened our understanding of these complex disorders. These clinical manifestations …

The current future understanding of inflammatory bowel disease

DK Podolsky - Best practice & research Clinical gastroenterology, 2002 - Elsevier
Accumulating evidence indicates that the inflammatory bowel diseases result from an
activation of immune and inflammatory responses initiated by a stimulation of the luminal …