Background Data are scarce for the lifetime risk of developing impaired glucose metabolism,
including prediabetes, as are data for the risk of eventual progression from prediabetes to …

Background The prevalence of type 2 diabetes is increasing rapidly, particularly among
younger age groups. Estimates suggest that people with diabetes die, on average, 6 years …

Background Diabetes incidence has increased and mortality has decreased greatly in the
USA, potentially leading to substantial changes in the lifetime risk of diabetes. We aimed to …

Background Despite the increased risk of cardiovascular disease and type 2 diabetes
associated with excess bodyweight, development of a clinically meaningful metric for health …

Background Diabetes is a major public health issue. Because lifetime risk, life expectancy,
and years of life lost are meaningful metrics for clinical decision making, we aimed to …

Prediabetes (intermediate hyperglycaemia) is a high-risk state for diabetes that is defined by
glycaemic variables that are higher than normal, but lower than diabetes thresholds. 5–10 …

Summary Prediabetes (or “intermediate hyperglycaemia”), based on glycaemic parameters
above normal but below diabetes thresholds is a high risk state for diabetes with an …

Summary Background Of the 84 million American adults with prediabetes, over 5 to 7 years,
about 28 million progress to type 2 diabetes. We aimed to assess whether a real-world …

Background Little is known about the timing of changes in glucose metabolism before
occurrence of type 2 diabetes. We aimed to characterise trajectories of fasting and postload …

Background Diabetes, particularly type 1 diabetes, at younger ages can be a largely
preventable cause of death with the correct health care and services. We aimed to evaluate …