Mutation of human short tandem repeats

JL Weber, C Wong - Human molecular genetics, 1993 - academic.oup.com
Abstract A total of 20,000 parent-offspring transfers of alleles were examined through the
genotyping within 40 CEPH reference families of 28 short tandem repeat polymorphisms …

Genetic variation at five trimeric and tetrameric tandem repeat loci in four human population groups

AL Edwards, HA Hammond, L Jin, CT Caskey… - Genomics, 1992 - Elsevier
Trimeric and tetrameric short tandem repeats (STRs) represent a rich source of highly
polymorphic markers in the human genome that may be studied with the polymerase chain …

[HTML][HTML] Mutation rate in human microsatellites: influence of the structure and length of the tandem repeat

B Brinkmann, M Klintschar, F Neuhuber… - The American Journal of …, 1998 - cell.com
Summary In 10,844 parent/child allelic transfers at nine short-tandem-repeat (STR) loci, 23
isolated STR mismatches were observed. The parenthood in each of these cases was highly …

Simple tandem DNA repeats and human genetic disease.

GR Sutherland, RI Richards - Proceedings of the National …, 1995 - National Acad Sciences
The human genome contains many repeated DNA sequences that vary in complexity of
repeating unit from a single nucleotide to a whole gene. The repeat sequences can be …

[HTML][HTML] Long homozygous chromosomal segments in reference families from the centre d'Etude du polymorphisme humain

KW Broman, JL Weber - The American Journal of Human Genetics, 1999 - cell.com
Using genotypes from nearly 8,000 short tandem-repeat polymorphisms typed in eight of the
reference families from the Centre d'Étude du Polymorphisme Humain (CEPH), we identified …

Isolation and chromosomal assignment of 100 highly informative human simple sequence repeat polymorphisms

TJ Hudson, M Engelstein, MK Lee, EC Ho… - Genomics, 1992 - Elsevier
One hundred highly informative simple sequence repeat (SSR) polymorphisms have been
isolated and mapped to specific human chromosomes by somatic cell hybrid analysis …

DNA typing and genetic mapping with trimeric and tetrameric tandem repeats.

A Edwards, A Civitello, HA Hammond… - American journal of …, 1991 - ncbi.nlm.nih.gov
Tandemly reiterated sequences represent a rich source of highly polymorphic markers for
genetic linkage, mapping, and personal identification. Human trimeric and tetrameric short …

A polymorphic X-linked tetranucleotide repeat locus displaying a high rate of new mutation: implications for mechanisms of mutation at short tandem repeat loci

MM Mahtani, HF Willard - Human molecular genetics, 1993 - academic.oup.com
We report a high rate of new mutation at a short tandem repeat sequence polymorphism
(STR, microsatellite) at locus DXS981 on the proximal long arm of the human X …

Isolation of human simple repeat loci by hybridization selection

JAL Armour, R Neumann, S Gobert… - Human molecular …, 1994 - academic.oup.com
We have isolated short tandem repeat arrays from the human genome, using a rapid method
involving filter hybridization to enrich for tri-or tetranucleotlde tandem repeats. About 30% of …

Improved set of short-tandem-repeat polymorphisms for screening the human genome.

B Yuan, D Vaske, JL Weber, J Beck… - American Journal of …, 1997 - ncbi.nlm.nih.gov
Short-tandem-repeat (microsatellite) DNA polymor-phisms are widely used for screening the
human and other genomes in initial linkage mapping. Since the average spacing between …