Frequency and distribution of tuberculosis resistance-associated mutations between Mumbai, Moldova, and Eastern Cape
Molecular diagnostic assays, with their ability to rapidly detect resistance-associated
mutations in bacterial genes, are promising technologies to control the spread of drug …
mutations in bacterial genes, are promising technologies to control the spread of drug …
Evaluation of pyrosequencing for detecting extensively drug-resistant Mycobacterium tuberculosis among clinical isolates from four high-burden countries
K Ajbani, SYG Lin, C Rodrigues… - Antimicrobial agents …, 2015 - Am Soc Microbiol
Reliable molecular diagnostics, which detect specific mutations associated with drug
resistance, are promising technologies for the rapid identification and monitoring of drug …
resistance, are promising technologies for the rapid identification and monitoring of drug …
Prevalence of and molecular basis for tuberculosis drug resistance in the Republic of Georgia: validation of a QIAplex system for detection of drug resistance-related …
M Gegia, N Mdivani, RE Mendes, H Li… - Antimicrobial agents …, 2008 - Am Soc Microbiol
We developed a QIAplex system for the simultaneous detection of 24 Mycobacterium
tuberculosis gene mutations responsible for resistance to isoniazid (INH), rifampin (RIF) …
tuberculosis gene mutations responsible for resistance to isoniazid (INH), rifampin (RIF) …
[HTML][HTML] Frequency and patterns of first-and second-line drug resistance-conferring mutations in Mycobacterium tuberculosis isolated from pulmonary tuberculosis …
Objectives Tuberculosis (TB) is a preventable and treatable infectious disease, but the
continuing emergence and spread of multidrug-resistant TB is threatening global TB control …
continuing emergence and spread of multidrug-resistant TB is threatening global TB control …
[HTML][HTML] Sequence analysis for detection of drug resistance in Mycobacterium tuberculosis complex isolates from the Central Region of Cameroon
EM Tekwu, LK Sidze, JPA Assam, JC Tedom… - BMC microbiology, 2014 - Springer
Background The potential of genetic testing to rapidly diagnose drug resistance has lead to
the development of new diagnostic assays. However, prior to implementation in a given …
the development of new diagnostic assays. However, prior to implementation in a given …
Detection of first-and second-line drug resistance in Mycobacterium tuberculosis clinical isolates by pyrosequencing
A Engström, N Morcillo, B Imperiale… - Journal of clinical …, 2012 - Am Soc Microbiol
Conventional phenotypic drug susceptibility testing (DST) methods for Mycobacterium
tuberculosis are laborious and very time-consuming. Early detection of drug-resistant …
tuberculosis are laborious and very time-consuming. Early detection of drug-resistant …
Isoniazid and rifampicin resistance mutations and their effect on second-line anti-tuberculosis treatment
D Abate, Y Tedla, D Meressa… - The International Journal …, 2014 - ingentaconnect.com
SETTING: St Peter's TB Specialized Hospital, Addis Ababa, Ethiopia. OBJECTIVE: To
estimate the prevalence of mutations that cause resistance to isoniazid (INH) and rifampicin …
estimate the prevalence of mutations that cause resistance to isoniazid (INH) and rifampicin …
Occurrence of Diverse Mutations in Isoniazid- and Rifampicin-Resistant Mycobacterium tuberculosis Isolates from Autochthonous and Immigrant Populations of Saudi …
B Varghese, M Shoukri, Z Memish… - Microbial drug …, 2014 - liebertpub.com
For the first time in Saudi Arabia, the impact of a patient's ethnic background on mutations
conferring resistance to rifampicin (RIF) and isoniazid (INH) in Mycobacterium tuberculosis …
conferring resistance to rifampicin (RIF) and isoniazid (INH) in Mycobacterium tuberculosis …
Molecular detection of mutations associated with first-and second-line drug resistance compared with conventional drug susceptibility testing of Mycobacterium …
PJ Campbell, GP Morlock, RD Sikes… - Antimicrobial agents …, 2011 - Am Soc Microbiol
The emergence of multi-and extensively drug-resistant tuberculosis is a significant
impediment to the control of this disease because treatment becomes more complex and …
impediment to the control of this disease because treatment becomes more complex and …
[HTML][HTML] Drug resistance-conferring mutations in Mycobacterium tuberculosis from pulmonary tuberculosis patients in Southwest Ethiopia
M Tadesse, D Aragaw, B Dimah, F Efa… - International journal of …, 2016 - Elsevier
Objective/background The nature and frequency of mutations in rifampicin (RIF) and
isoniazid (INH) resistant Mycobacterium tuberculosis isolates vary considerably according to …
isoniazid (INH) resistant Mycobacterium tuberculosis isolates vary considerably according to …