Because stress may underlie the presence of depressive episodes, strategies to produce
protection against or to reverse the effects of stress on neuroplasticity and behavior are …

Environmental Enrichment (EE) improves cognitive function and enhances brain plasticity,
while chronic stress increases emotionality, impairs learning and memory, and has adverse …

Major depression is a highly prevalent mental disorder and environmental factors have been
strongly implicated in its pathophysiology. Clinical studies have demonstrated that stress or …

Physical–cognitive activity has long-lasting beneficial effects on the brain and on behavior.
Environmental enrichment (EE) induces brain activity known to influence the behavior of …

Chronic stress drives behavioral and physiological changes associated with numerous
psychiatric disease states. In rodents, the vast majority of chronic stress models involve …

Depression is a neuropsychiatric disorder with a high impact on the worldwide population.
To overcome depression, antidepressant drugs are the first line of treatment. However, pre …

Chronic stress decreases neurogenesis in the adult brain, while exposure to enriched
environment (EE) increases it. Recent studies demonstrate the ability of EE to ameliorate …

The subgranular zone of the adult hippocampal dentate gyrus contains a pool of neural stem
cells that continuously divide and differentiate into functional granule cells. It has been …

Environmental enrichment (EE) is an experimental animal model that enhances an animal's
opportunity to interact with sensory, motor, and social stimuli, compared to standard …

Convincing evidence shows that stress is associated with the development and course of
psychiatric and metabolic disorders. The hypothalamic-pituitary-adrenal (HPA) axis …