Beyond interferon side effects: what residual barriers exist to DAA hepatitis C treatment for people who inject drugs?

A Madden, M Hopwood, J Neale, C Treloar - PloS one, 2018 - journals.plos.org
Recent advances in the efficacy and tolerability of hepatitis C treatments and the introduction
of a universal access scheme for the new Direct Acting Antiviral (DAA) therapies in March …

Economic evaluation of direct-acting antiviral therapy in chronic hepatitis C.

ZF Gellad, SD Reed, AJ Muir - Antiviral therapy, 2012 - europepmc.org
In 2011, the protease inhibitors boceprevir and telaprevir were approved in the United
States and European Union for the treatment of hepatitis C infection. While remarkably …

[HTML][HTML] New hope for hepatitis C virus: Summary of global epidemiologic changes and novel innovations over 20 years

BB Dennis, L Naji, Y Jajarmi, A Ahmed… - World journal of …, 2021 - ncbi.nlm.nih.gov
Hepatitis C virus (HCV) is a global health concern associated with significant morbidity and
mortality. Before the approval of second-generation direct-acting antiviral agents (DAAs) …

[PDF][PDF] Direct‐acting antiviral drug approvals for treatment of chronic hepatitis C virus infection: scientific and regulatory approaches to clinical trial designs

P Mishra, J Murray, D Birnkrant - Hepatology, 2015 - Wiley Online Library
Therapeutic options for treatment of chronic hepatitis C have improved substantially since
the approval of direct‐acting antiviral agents (DAAs). Several interferon (IFN)‐free or IFN …

Hep C Calculator: an online tool for cost-effectiveness analysis of DAAs

J Chhatwal, Q Chen, ED Bethea, MA Ladd… - The Lancet …, 2018 - thelancet.com
An estimated 71 million people are infected with hepatitis C virus (HCV) globally, resulting in
about 400 000 deaths each year. 1 The availability of direct-acting antivirals (DAAs) offers …

Planning and prioritizing direct-acting antivirals treatment for HCV patients in countries with limited resources: lessons from the Egyptian experience

A Elsharkawy, M El-Raziky, W El-Akel, K El-Saeed… - Journal of …, 2018 - Elsevier
Background and Aims The introduction of direct-acting antivirals for hepatitis C virus (HCV)
in Egypt led to massive treatment uptake, with Egypt's national HCV treatment program …

Hepatitis C virus treatment: simplifying the simple and optimizing the difficult

O Falade-Nwulia, MS Sulkowski - The Journal of Infectious …, 2020 - academic.oup.com
The availability of safe, efficacious, oral direct-acting antivirals (DAAs) have ushered in a
new era of hepatitis C treatment with potential to eliminate hepatitis C as a public health …

Universal medicine access through lump-sum remuneration—Australia's approach to hepatitis C

S Moon, E Erickson - New England Journal of Medicine, 2019 - Mass Medical Soc
Universal Access through Lump-Sum Remuneration Australia's agreement to spend about 1
billion Australian dollars (US $766 million) over 5 years in exchange for an unlimited volume …

'Beyond the willing & the waiting'—the role of peer-based approaches in hepatitis C diagnosis & treatment

C Henderson, A Madden, J Kelsall - International Journal of Drug Policy, 2017 - Elsevier
This commentary seeks to examine the role, value and importance of peer-based
programmatic approaches for ensuring the effective roll-out of the new hepatitis C (HCV) …

Effect of voluntary licences for hepatitis C medicines on access to treatment: a difference-in-differences analysis

B Simmons, GS Cooke, M Miraldo - The Lancet Global Health, 2019 - thelancet.com
Background Voluntary licences are increasingly being used to expand access to patented
essential medicines in low-income and middle-income countries (LMICs). Since 2014, non …