Fundamentals and developments in fluorescence-guided cancer surgery
JSD Mieog, FB Achterberg, A Zlitni… - Nature reviews Clinical …, 2022 - nature.com
Fluorescence-guided surgery using tumour-targeted imaging agents has emerged over the
past decade as a promising and effective method of intraoperative cancer detection. An …
past decade as a promising and effective method of intraoperative cancer detection. An …
Optical molecular imaging for tumor detection and image-guided surgery
We have witnessed rapid development of fluorescence molecular imaging of solid tumors for
cancer diagnosis and image-guided surgery in the past decade. Many biomarkers unique to …
cancer diagnosis and image-guided surgery in the past decade. Many biomarkers unique to …
Development of tumor-targeted near infrared probes for fluorescence guided surgery
LE Kelderhouse, V Chelvam, C Wayua… - Bioconjugate …, 2013 - ACS Publications
Complete surgical resection of malignant disease is the only reliable method to cure cancer.
Unfortunately, quantitative tumor resection is often limited by a surgeon's ability to locate all …
Unfortunately, quantitative tumor resection is often limited by a surgeon's ability to locate all …
Molecular probes for fluorescence image-guided cancer surgery
R Ito, M Kamiya, Y Urano - Current Opinion in Chemical Biology, 2022 - Elsevier
In cancer surgery, complete surgical resection of tumor lesions is critical to optimize the
outcome. However, it is sometimes difficult to distinguish the boundary between tumor and …
outcome. However, it is sometimes difficult to distinguish the boundary between tumor and …
[HTML][HTML] Challenges and opportunities to penetrate the blood-brain barrier for brain cancer therapy
DH Upton, C Ung, SM George, M Tsoli, M Kavallaris… - Theranostics, 2022 - ncbi.nlm.nih.gov
Despite significant advances in research, the prognosis for both primary and secondary
brain cancers remains poor. The blood-brain barrier (BBB) is a complex and unique semi …
brain cancers remains poor. The blood-brain barrier (BBB) is a complex and unique semi …
[HTML][HTML] Intraoperative imaging-guided cancer surgery: from current fluorescence molecular imaging methods to future multi-modality imaging technology
Cancer is a major threat to human health. Diagnosis and treatment using precision medicine
is expected to be an effective method for preventing the initiation and progression of cancer …
is expected to be an effective method for preventing the initiation and progression of cancer …
Fluorescence-guided surgery with live molecular navigation—a new cutting edge
QT Nguyen, RY Tsien - Nature reviews cancer, 2013 - nature.com
A glowing new era in cancer surgery may be dawning. Using fluorescently labelled markers,
surgical molecular navigation means that tumours and nerves can be displayed in real time …
surgical molecular navigation means that tumours and nerves can be displayed in real time …
Dual-targeting upconversion nanoprobes across the blood–brain barrier for magnetic resonance/fluorescence imaging of intracranial glioblastoma
Surgical resection, one of the main clinical treatments of intracranial glioblastoma, bears the
potential risk of incomplete excision due to the inherent infiltrative character of the …
potential risk of incomplete excision due to the inherent infiltrative character of the …
[HTML][HTML] Optical image-guided surgery—where do we stand?
S Keereweer, JDF Kerrebijn, PBAA Van Driel… - Molecular Imaging and …, 2011 - Springer
In cancer surgery, intra-operative assessment of the tumor-free margin, which is critical for
the prognosis of the patient, relies on the visual appearance and palpation of the tumor …
the prognosis of the patient, relies on the visual appearance and palpation of the tumor …
Molecular targeted NIR-II probe for image-guided brain tumor surgery
Optical imaging strategies for improving delineation of glioblastoma (GBM) is highly desired
for guiding surgeons to distinguish cancerous tissue from healthy and precious brain tissue …
for guiding surgeons to distinguish cancerous tissue from healthy and precious brain tissue …