The oxytocin receptor was first identified using a pharmacological ligandbinding assay in the
rat myometrium (Soloff and Swartz 1973). Its peptide ligand, oxytocin, belongs to the …

Parturition is the final and most dramatic event during pregnancy. During the parturition, the
regular and cooperative contraction of myometrium is necessary for expulsion of the fetus …

The neurohypophyseal nonapeptide oxytocin (OT) is the main hormone responsible for the
initiation of labor; uterus contraction can be enhanced by application of oxytocin or …

A number of structurally novel cyclic hexapeptides have been characterized as potent and
selective oxytocin (OT) antagonists in vitro. As a representative of this class of compounds, L …

We describe here the binding and functional properties of a cloned human oxytocin receptor
(OTR). We established a transient OTR expression system on COS-1 cells, which do not …

We report the solid-phase synthesis and receptor-binding properties of eleven oxytocin
analogs (Mpa-Xxx-Ile-Gln-Asn-Cys-Sar-Arg-Gly-NH 2) containing non-coded amino acids in …

[3 H] Oxytocin, incubated with mammary tissue from the lactating rat, was bound specifically
to three particulate fractions obtained by homogenization and centrifugation at 1,000 …

[3H]‐oxytocin was used to characterize the oxytocin receptor found in human uterine smooth
muscle cells (USMC). Specific binding of [3H]‐oxytocin to USMC plasma membranes was …

The oxytocin antagonist [Mpa 1, d-Tyr (Et) 2, Thr 4, Orn 8]-oxytocin has been successfully
used for treating premature labour. The interactions of this antagonist with …

We investigated the mechanisms that regulate the efficacy of agonists in the arginine‐
vasopressin (AVP)/oxytocin (OT) receptor system. In this paper, we present evidence that …