Chondroitin sulfate proteoglycans (CSPGs) are upregulated after CNS lesions, where they
inhibit axon regeneration. In order for axon growth and regeneration to occur, surface …

Chondroitin sulfate proteoglycans (CSPGs) are upregulated in the CNS after injury and
participate in the inhibition of axon regeneration mainly through their glycosaminoglycan …

In the developing or regenerating nervous system, migrating growth cones are exposed to
regulatory molecules that positively and/or negatively affect guidance. Chondroitin sulfate …

Aggrecan is one of the major chondroitin sulfate proteoglycans (CSPGs) expressed in the
central nervous system. The signaling pathways activated downstream of cell interaction …

The primary mediators of cell migration during development, wound healing and metastasis,
are receptors of the integrin family. In the developing and regenerating nervous system …

Chondroitin sulfate proteoglycans (CSPGs) are a family of extracellular matrix molecules
with various functions in regulating tissue morphogenesis, cell division, and axon guidance …

The extension of axons through the major inhibitory component of the glial scar, chondroitin
sulfate proteoglycans (CSPGs), remains a key obstacle for regeneration following spinal …

Chondroitin sulfate proteoglycans (CSPGs) represent a major barrier to regenerating axons
in the central nervous system (CNS), but the structural diversity of their polysaccharides has …

CNS damage often results in demyelination of spared axons due to oligodendroglial cell
death and dysfunction near the injury site. Although new oligodendroglia are generated …

In animal models, transplantation of bone marrow stromal cells (MSC) into the spinal cord
following injury enhances axonal regeneration and promotes functional recovery. How these …