Identification of an exosomal miRNA-mRNA regulatory network contributing to methotrexate efficacy

M Zhang, Z Niu, Q Huang, L Han, J Du, J Liang… - International …, 2024 - Elsevier
Objective Methotrexate (MTX) is an economic and effective medicine treatment for psoriasis.
Extracellular vesicle (EV) miRNA biomarkers related to its efficiency have been identified in …

Circulating microRNA profile unveils mechanisms of action of acitretin for psoriasis vulgaris

L Chen, J Li, Y Yao, S Wang, S Zheng, X Ju… - …, 2021 - Taylor & Francis
Psoriasis vulgaris is a common chronic and recurrent inflammatory skin disease. In clinical
practice, acitretin is the first-line treatment drug for psoriasis vulgaris. MicroRNAs (miRNAs) …

Keratinocyte-derived circulating microRNAs in extracellular vesicles: a novel biomarker of psoriasis severity and potential therapeutic target

YJ Park, DC Kim, SJ Lee, HS Kim, JY Pak, J Kim… - Journal of Translational …, 2024 - Springer
Background Psoriasis is a chronic inflammatory disorder characterized by pathogenic
hyperproliferation of keratinocytes and immune dysregulation. Currently, objective …

[HTML][HTML] Role of an imbalanced miRNAs axis in pathogenesis of psoriasis: novel perspectives based on review of the literature

MJ Wang, YY Xu, RY Huang, XM Chen, HM Chen… - Oncotarget, 2017 - ncbi.nlm.nih.gov
BACKGROUND Specific profile of microRNAs (miRNAs, miR) expressed in psoriasis has
been identified in the past few years, while the studies on roles and molecular mechanisms …

TargetScore used to reveal potential targets of miRNA203 and miRNA-146a in psoriasis by integrating microRNA overexpression and microarray data

HX Chen, YS Liu, XJ Zhang - Medicine, 2018 - journals.lww.com
Objective: Systematic tracking of microRNA (miRNA) targets remains a challenge. In our
work, we aimed to use TargetScore to investigate the potential targets of miRNA203 and …

[HTML][HTML] Is Mir-205 a possible biomarker for evaluating treatment response in psoriasis?

C Mihu, CA Popescu, D Cenariu, Ş Vesa… - Journal of Medicine …, 2024 - ncbi.nlm.nih.gov
Psoriasis is a chronic skin disease that affects a significant number of patients and can
severely impair quality of life. Although the diagnosis is normally clinical, paraclinical …

Identification of serum exosomal miRNA biomarkers for diagnosis of Rheumatoid arthritis

J Gong, X Zhang, A Khan, J Liang, T Xiong… - International …, 2024 - Elsevier
Background Rheumatoid arthritis (RA) is an autoimmune disorder characterized by
inflammation-induced joint damage, which can cause lasting disability. Therefore, early …

Deep sequencing of plasma exosomal microRNA level in psoriasis vulgaris patients

XM Chen, DN Yao, MJ Wang, XD Wu, JW Deng… - Frontiers in …, 2022 - frontiersin.org
Psoriasis is a chronic skin disease affecting 1% to 3% of the world population. Psoriasis
vulgaris (PV) is the most common form of psoriasis. PV patients suffer from inflamed, pruritic …

miRNA-Mediated Epigenetic Regulation of Treatment Response in RA Patients—A Systematic Review

A Mucientes, JM Lisbona, N Mena-Vázquez… - International Journal of …, 2022 - mdpi.com
This study aimed to evaluate the role of microRNAs (miRNA) as biomarkers of treatment
response in rheumatoid arthritis (RA) patients through a systematic review of the literature …

MiR-193b-3p–ERBB4 axis regulates psoriasis pathogenesis via modulating cellular proliferation and inflammatory-mediator production of keratinocytes

C Huang, W Zhong, X Ren, X Huang, Z Li… - Cell Death & …, 2021 - nature.com
Psoriasis is an auto-inflammatory skin disease characterized by abnormal activation of
epidermal keratinocytes, aberrant neovascularization, and dysregulation of immune cells …