The trajectory of disturbed resting‐state cerebral function in Parkinson's disease at different Hoehn and Yahr stages

CY Luo, XY Guo, W Song, Q Chen, J Yang… - Human brain …, 2015 - Wiley Online Library
Objective We aim to investigate the disturbance of neural network associated with the
different clinical stages of Parkinson's disease (PD). Method We recruited 80 patients at …

Alterations of Cortical Structure and Neurophysiology in Parkinson's Disease Are Aligned with Neurochemical Systems

AI Wiesman, J da Silva Castanheira, EA Fon… - Annals of …, 2024 - Wiley Online Library
Objective Parkinson's disease (PD) affects the structural integrity and neurophysiological
signaling of the cortex. These alterations are related to the motor and cognitive symptoms of …

Distinct functional and macrostructural brain changes in P arkinson's disease and multiple system atrophy

PJ Planetta, AS Kurani, P Shukla… - Human brain …, 2015 - Wiley Online Library
Parkinson's disease (PD) and the parkinsonian variant of multiple system atrophy (MSAp)
are neurodegenerative disorders that can be difficult to differentiate clinically. This study …

[HTML][HTML] Compensatory striatal–cerebellar connectivity in mild–moderate Parkinson's disease

AC Simioni, A Dagher, LK Fellows - NeuroImage: Clinical, 2016 - Elsevier
Dopamine depletion in the putamen is associated with altered motor network functional
connectivity in people with Parkinson's disease (PD), but the functional significance of these …

[HTML][HTML] Pattern of reduced functional connectivity and structural abnormalities in Parkinson's disease: an exploratory study

RP Guimarães, MC Arci Santos, A Dagher… - Frontiers in …, 2017 - frontiersin.org
Background MRI brain changes in Parkinson's disease (PD) are controversial. Objectives
We aimed to describe structural and functional changes in PD. Methods Sixty-six patients …

A computational model‐based analysis of basal ganglia pathway changes in Parkinson's disease inferred from resting‐state fMRI

O Maith, F Villagrasa Escudero… - European Journal of …, 2021 - Wiley Online Library
Previous computational model‐based approaches for understanding the dynamic changes
related to Parkinson's disease made particular assumptions about Parkinson's disease …

Functional and structural changes in gray matter of parkinson's disease patients with mild cognitive impairment

B Chen, S Wang, W Sun, X Shang, H Liu, G Liu… - European journal of …, 2017 - Elsevier
Background and purpose Cognitive impairment is a common non-motor complication of
Parkinson's disease (PD). To investigate cognitive-related changes of gray matter (GM) …

[HTML][HTML] The study of brain functional connectivity in Parkinson's disease

L Gao, T Wu - Translational neurodegeneration, 2016 - Springer
Parkinson's disease (PD) is a neurodegenerative disorder primarily affecting the aging
population. The neurophysiological mechanisms underlying parkinsonian symptoms remain …

Role of hyperactive cerebellum and motor cortex in Parkinson's disease

H Yu, D Sternad, DM Corcos, DE Vaillancourt - Neuroimage, 2007 - Elsevier
Previous neuroimaging studies have found hyperactivation in the cerebellum and motor
cortex and hypoactivation in the basal ganglia in patients with Parkinson's disease (PD) but …

Early cortical gray matter loss and cognitive correlates in non-demented Parkinson's patients

EY Lee, S Sen, PJ Eslinger, D Wagner… - Parkinsonism & related …, 2013 - Elsevier
Background Whereas the motor dysfunction in Parkinson's disease (PD) has been related to
deficits in basal ganglia (BG) structures, neural correlates of cognitive changes remain to be …