Targeted therapeutics and nanodevices for vascular drug delivery: Quo vadis?

VR Muzykantov - IUBMB life, 2011 - Wiley Online Library
This issue of the journal is dedicated to targeted delivery of therapeutics in the vasculature,
an approach that holds promise to optimize treatment of diverse pathological conditions …

Nanomedicine approaches in vascular disease: a review

AS Gupta - Nanomedicine: Nanotechnology, Biology and Medicine, 2011 - Elsevier
Nanomedicine approaches have revolutionized the treatment of cancer and vascular
diseases, where the limitations of rapid nonspecific clearance, poor biodistribution and …

Vascular‐targeted nanocarriers: design considerations and strategies for successful treatment of atherosclerosis and other vascular diseases

WJ Kelley, H Safari, G Lopez‐Cazares… - Wiley …, 2016 - Wiley Online Library
Vascular‐targeted nanocarriers are an attractive option for the treatment of a number of
cardiovascular diseases, as they allow for more specific delivery and increased efficacy of …

Targeting drug delivery in the vascular system: Focus on endothelium

PM Glassman, JW Myerson, LT Ferguson… - Advanced drug delivery …, 2020 - Elsevier
The bloodstream is the main transporting pathway for drug delivery systems (DDS) from the
site of administration to the intended site of action. In many cases, components of the …

Targeted drug delivery for cardiovascular and Cerebrovascular Diseases

J Luan, G Zhai - Current Drug Targets, 2016 - ingentaconnect.com
Cardiovascular and cerebrovascular diseases (CCVD) are a major and increasing health
burden worldwide. Although treatments have been made a certain progress, the …

Dynamic and cellular interactions of nanoparticles in vascular-targeted drug delivery

RB Huang, S Mocherla, MJ Heslinga… - Molecular membrane …, 2010 - Taylor & Francis
Vascular-targeted drug delivery systems could provide more efficient and effective
pharmaceutical interventions for treating a variety of diseases including cardiovascular …

Nanosystems in drug targeting: opportunities and challenges

JK Vasir, MK Reddy, VD Labhasetwar - Current Nanoscience, 2005 - ingentaconnect.com
The long cherished goal of targeting drugs to specific sites in the body, where the
pharmacological action is desired and sparing other tissues has been actively pursued all …

Cell and organ drug targeting

D Ghosh, N Upmanyu, T Shukla… - Nanomaterials for Drug …, 2019 - Elsevier
Conventional drug therapies suffer from several limitations most prominently the
pharmacokinetic alterations in biological systems, which result in decreased bioavailability …

Pharmaceutical nanotechnology: overcoming drug delivery challenges in contemporary medicine

S Ganta, A Singh, TP Coleman, D Williams… - Nanomedicine: Principles …, 2014 - Springer
This review discusses the challenges associated with drug delivery and benefits of
employing nanosystems in the delivery of small and macromolecular drugs. Poor …

Vascular nanomedicine: current status, opportunities, and challenges

M Sun, AS Gupta - Seminars in thrombosis and hemostasis, 2020 - thieme-connect.com
The term “nanotechnology” was coined by Norio Taniguchi in the 1970s to describe the
manipulation of materials at the nano (10− 9) scale, and the term “nanomedicine” was put …