[HTML][HTML] Quercetin loaded cationic solid lipid nanoparticles in a mucoadhesive in situ gel—a novel intravesical therapy tackling bladder cancer

S Shawky, S Makled, A Awaad, N Boraie - Pharmaceutics, 2022 - mdpi.com
The study aim was to develop an intravesical delivery system of quercetin for bladder cancer
management in order to improve drug efficacy, attain a controlled release profile and extend …

Treating acute cystitis with biodegradable micelle-encapsulated quercetin

BL Wang, X Gao, K Men, J Qiu, B Yang… - International journal …, 2012 - Taylor & Francis
Intravesical application of an anti-inflammatory drug is an efficient strategy for acute cystitis
therapy. Quercetin (QU) is a potent anti-inflammatory agent; however, its poor water …

Catechol-functionalized alginate nanoparticles as mucoadhesive carriers for intravesical chemotherapy

N Sahatsapan, T Ngawhirunpat, T Rojanarata… - AAPS …, 2020 - Springer
This research aimed to synthesize and evaluate mucoadhesive catechol-functionalized
alginate (Cat-Alg) nanoparticles (NPs) for bladder cancer. Cat-Alg was synthesized using …

Gemcitabine hydrochloride microspheres used for intravesical treatment of superficial bladder cancer: a comprehensive in vitro/ex vivo/in vivo evaluation

SY Karavana, ZA Şenyiğit, Ç Çalışkan… - Drug design …, 2018 - Taylor & Francis
Introduction Bladder cancer is responsible for more than 130,000 deaths annually
worldwide. Intravesical delivery of chemotherapeutic agents provides effective drug …

Design and evaluation of an intravesical delivery system for superficial bladder cancer: preparation of gemcitabine HCl-loaded chitosan–thioglycolic acid …

Z Ay Şenyiğit, SY Karavana… - International journal …, 2015 - Taylor & Francis
This study aimed to develop an intravesical delivery system of gemcitabine HCl for
superficial bladder cancer in order to provide a controlled release profile, to prolong the …

Lipid colloidal carriers for improvement of anticancer activity of orally delivered quercetin: formulation, characterization and establishing in vitro–in vivo advantage

AS Jain, SM Shah, MS Nagarsenker… - Journal of …, 2013 - ingentaconnect.com
Novel lipid nanocarriers, GeluPearl (GP) comprising of Precirol ATO 5 lipid nanoparticles
with (GPNLC) or without oil (GPSLN), loaded with Quercetin (QR), were successfully …

Quercetin-loaded solid lipid nanoparticle dispersion with improved physicochemical properties and cellular uptake

A Vijayakumar, R Baskaran, YS Jang, SH Oh… - Aaps Pharmscitech, 2017 - Springer
The objective of this study was to formulate and characterize properties of solid lipid
nanoparticle (SLN) dispersion containing quercetin. SLN was prepared by ultrasonication …

Design and characterization of mucoadhesive gelatin-ethylcellulose microparticles for the delivery of curcumin to the bladder

MB Oliveira, JB da Silva, MC Montanha… - Current drug …, 2018 - ingentaconnect.com
Background: Bladder cancer is the second type of malignant carcinoma of the urinary tract.
The treatment is time-consuming and requires maintenance doses of the drug for long …

Characterization and biodistribution in vivo of quercetin-loaded cationic nanostructured lipid carriers

L Liu, Y Tang, C Gao, Y Li, S Chen, T Xiong, J Li… - Colloids and Surfaces B …, 2014 - Elsevier
Nanobiotechnology has been recently viewed as a promising strategy to improve therapy
efficacy by promoting the accumulation of hydrophobic bioactive compounds in tissues. The …

Preparation and characterization of lipid based nanosystems for topical delivery of quercetin

S Bose, B Michniak-Kohn - European Journal of Pharmaceutical Sciences, 2013 - Elsevier
The main objective of this study was to evaluate the potential of lipid nanosystems for topical
delivery of the naturally occurring flavonoid quercetin. These lipid based nanosystems were …