Renin-angiotensin system alterations in the human Alzheimer's disease brain
S Ismael, G Mirzahosseini, HA Ahmed… - Journal of …, 2021 - content.iospress.com
Background: Understanding Alzheimer's disease (AD) in terms of its various
pathophysiological pathways is essential to unravel the complex nature of the disease …
pathophysiological pathways is essential to unravel the complex nature of the disease …
Higher angiotensin II type 1 receptor (AT1R) levels and activity in the postmortem brains of older persons with Alzheimer's disease
C Cosarderelioglu, CJ George… - Alzheimer's & …, 2021 - Wiley Online Library
Background Alzheimer's disease (AD) is the most common cause of dementia. Although
multiple potential etiologies have been proposed, no clear aging‐related etiological …
multiple potential etiologies have been proposed, no clear aging‐related etiological …
Angiotensin-converting enzyme 2 is reduced in Alzheimer's disease in association with increasing amyloid-β and tau pathology
PG Kehoe, S Wong, N Al Mulhim, LE Palmer… - Alzheimer's research & …, 2016 - Springer
Background Hyperactivity of the classical axis of the renin-angiotensin system (RAS),
mediated by angiotensin II (Ang II) activation of the angiotensin II type 1 receptor (AT1R), is …
mediated by angiotensin II (Ang II) activation of the angiotensin II type 1 receptor (AT1R), is …
Brain angiotensin II and angiotensin IV receptors as potential Alzheimer's disease therapeutic targets
J Royea, E Hamel - Geroscience, 2020 - Springer
Alzheimer's disease (AD) is a neurodegenerative disorder that is multifactorial in nature. Yet,
despite being the most common form of dementia in the elderly, AD's primary cause remains …
despite being the most common form of dementia in the elderly, AD's primary cause remains …
Angiotensins in Alzheimer's disease–friend or foe?
The renin–angiotensin system (RAS) is an important regulator of blood pressure.
Observational and experimental studies suggest that alterations in blood pressure and …
Observational and experimental studies suggest that alterations in blood pressure and …
Angiotensin-III is increased in Alzheimer's disease in association with amyloid-β and tau pathology
PG Kehoe, E Hibbs, LE Palmer… - Journal of Alzheimer's …, 2017 - content.iospress.com
Hyperactivity of the renin-angiotensin system (RAS) is associated with the pathogenesis of
Alzheimer's disease (AD) believed to be mediated by angiotensin-II (Ang-II) activation of the …
Alzheimer's disease (AD) believed to be mediated by angiotensin-II (Ang-II) activation of the …
Renin-angiotensin system and Alzheimer's disease pathophysiology: from the potential interactions to therapeutic perspectives
VT Ribeiro, LC de Souza… - Protein and Peptide …, 2020 - ingentaconnect.com
New roles of the Renin-Angiotensin System (RAS), apart from fluid homeostasis and Blood
Pressure (BP) regulation, are being progressively unveiled, since the discoveries of RAS …
Pressure (BP) regulation, are being progressively unveiled, since the discoveries of RAS …
Circulating angiotensin-(1–7) Is reduced in Alzheimer's disease patients and correlates with white matter abnormalities: results from a pilot study
VT Ribeiro, TM Cordeiro, RS Filha, LG Perez… - Frontiers in …, 2021 - frontiersin.org
Introduction Alzheimer's disease (AD) is the leading cause of dementia worldwide. Despite
the extensive research, its pathophysiology remains largely unelucidated. Currently, more …
the extensive research, its pathophysiology remains largely unelucidated. Currently, more …
The renin-angiotensin system and the neurodegenerative diseases: a brief review
AF Almeida-Santos, LM Kangussu… - Protein and Peptide …, 2017 - ingentaconnect.com
Background: A large body of studies characterized the renal and cardiovascular effects of
the peptides of the renin-angiotensin system (RAS). We now recognize that, in addition to …
the peptides of the renin-angiotensin system (RAS). We now recognize that, in addition to …
Commentary (The Renin Angiotensin System in Alzheimer's Disease-Do Updates Highlight a Clinical and Biological Dichotomy?)
PG Kehoe, GK Wilcock - Current Alzheimer Research, 2006 - ingentaconnect.com
It is little over a year since Savaskan reviewed in Current Alzheimer Research, the possible
involvement of the Renin Angiotensin System (RAS) in Alzheimer's disease (AD)[1] …
involvement of the Renin Angiotensin System (RAS) in Alzheimer's disease (AD)[1] …