MicroRNA replacement therapy in cancer
H Mollaei, R Safaralizadeh… - Journal of cellular …, 2019 - Wiley Online Library
Despite the recent progress in cancer management approaches, the mortality rate of cancer
is still growing and there are lots of challenges in the clinics in terms of novel therapeutics …
is still growing and there are lots of challenges in the clinics in terms of novel therapeutics …
Targeted delivery of miRNA therapeutics for cardiovascular diseases: opportunities and challenges
RFJ Kwekkeboom, Z Lei, PA Doevendans… - Clinical …, 2014 - portlandpress.com
Dysregulation of miRNA expression has been associated with many cardiovascular
diseases in animal models, as well as in patients. In the present review, we summarize …
diseases in animal models, as well as in patients. In the present review, we summarize …
[HTML][HTML] Therapeutic advances of miRNAs: A preclinical and clinical update
C Chakraborty, AR Sharma, G Sharma… - Journal of advanced …, 2021 - Elsevier
Background miRNAs, a class of small endogenous RNAs, are one of the essential
biopharmaceuticals which are in commercial spans as next-generation medicine in recent …
biopharmaceuticals which are in commercial spans as next-generation medicine in recent …
MicroRNA therapeutics in cancer: current advances and challenges
Simple Summary Cancer is a complex disease associated with deregulation of numerous
genes. In addition, redundant cellular pathways limit efficiency of monotarget drugs in …
genes. In addition, redundant cellular pathways limit efficiency of monotarget drugs in …
microRNA therapies in cancer
SI Rothschild - Molecular and cellular therapies, 2014 - Springer
MicroRNAs (miRNAs or miRs) are a family of small non-coding RNA species that have been
implicated in the control of many fundamental cellular and physiological processes such as …
implicated in the control of many fundamental cellular and physiological processes such as …
MicroRNA-mediated regulation of differentiation and trans-differentiation in stem cells
MicroRNAs (miRNAs) are key components of a broadly conserved post-transcriptional
mechanism that controls gene expression by targeting mRNAs. miRNAs regulate diverse …
mechanism that controls gene expression by targeting mRNAs. miRNAs regulate diverse …
A comprehensive review of cancer MicroRNA therapeutic delivery strategies
A Forterre, H Komuro, S Aminova, M Harada - Cancers, 2020 - mdpi.com
In the field of molecular oncology, microRNAs (miRNAs) and their role in regulating
physiological processes and cancer pathogenesis have been a revolutionary discovery over …
physiological processes and cancer pathogenesis have been a revolutionary discovery over …
Getting miRNA therapeutics into the target cells for neurodegenerative diseases: a mini-review
MM Wen - Frontiers in molecular neuroscience, 2016 - frontiersin.org
miRNAs play important roles in modulating gene expression in varying cellular processes
and disease pathogenesis, including neurodegenerative diseases. Several miRNAs are …
and disease pathogenesis, including neurodegenerative diseases. Several miRNAs are …
[HTML][HTML] MicroRNA therapeutics: principles, expectations, and challenges
R Rupaimoole, HD Han, G Lopez-Berestein… - Chinese journal of …, 2011 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) are a class of highly abundant non-coding RNA molecules that are
involved in several biological processes. Many miRNAs are often deregulated in several …
involved in several biological processes. Many miRNAs are often deregulated in several …
MicroRNAs en route to the clinic: progress in validating and targeting microRNAs for cancer therapy
AL Kasinski, FJ Slack - Nature Reviews Cancer, 2011 - nature.com
In normal cells multiple microRNAs (miRNAs) converge to maintain a proper balance of
various processes, including proliferation, differentiation and cell death. miRNA …
various processes, including proliferation, differentiation and cell death. miRNA …