Proteomics technologies demonstrate enormous data-gathering capabilities to discover
disease-specific biomarkers in serum, plasma, urine, tissue and other biological samples …

The last few years have seen an unprecedented drive toward the application of proteomics
to resolving challenging biomedical and biochemical tasks. Separation techniques …

The sequencing of several organisms' genomes, including the human's one, has opened the
way for the so‐called postgenomic era, which is now routinely coined as “proteomics”. The …

Proteomics is the study of all or part of the protein complement of genes in an organism,
often involving the analysis of complex protein/peptide samples. Such complex samples are …

Column liquid chromatography (LC) increasingly is used as a complement to or replacement
for gel electrophoresis, but the coupling of two or more chromatographic modes generally is …

Two-dimensional liquid-chromatographic (LC) separation followed by mass spectrometric
(MS) analysis was examined for the identification of peptides in complex mixtures as an …

This review provides an introduction for the nonspecialist to proteomics and in particular the
major approaches available for global protein identification and quantification. Proteomics …

Mass spectrometry (MS) is the most comprehensive and versatile tool in large-scale
proteomics. In this review, we dissect the overall framework of the MS experiment into its key …

The limitations of 2-D gels for global proteomics have encouraged the development of
alternative approaches for identifying proteins in complicated mixtures, and determining …

Proteomics can be defined as the systematic analysis of proteins for their identity, quantity
and function. In contrast to a cell's static genome, the proteome is both complex and …