In the past decade, shotgun proteomic analysis has been utilized extensively to answer
complex biological questions. New challenges arise in large scale proteomic profiling when …

We present some current definitions related to functional and structural proteomics and the
human proteome, and we review the following aspects of proteome analysis: Classical 2-D …

The complexity of the human serum proteome is attributed to both a large dynamic range of
protein abundance, as much as 10 orders of magnitude, and a disproportionate few dozens …

Proteomics is defined as the protein complement of the genome and involves the complete
analysis of all the proteins in a given sample [1, 2]. Several technologies are involved, and …

The objective of this study was to determine if liquid chromatography mass spectrometry
(LC/MS) data of tryptic digests of proteins can be used for quantitation. In theory, the peak …

Proteomics is a large-scale study of proteins, aiming at the description and characterization
of all expressed proteins in biological systems. The expressed proteins are typically highly …

There are probably no biological samples that did more to spur interest in proteomics than
serum and plasma. The belief was that comparing the proteomes of these samples obtained …

Introducing Proteomics gives a concise and coherent overview of every aspect of current
proteomics technology, which is a rapidly developing field that is having a major impact …

We developed a gel‐and label‐free proteomics platform for comparative studies of human
serum. The method involves the depletion of the six most abundant proteins, protein …

Multidimensional protein identification technology (MudPIT)(1) developed as a method to
analyze the highly complex samples necessary for large-scale proteome analysis by …