Background: Antibodies to aquaporin-4 (AQP4-Ab), known as NMO-IgG, are a sensitive and
specific marker for neuromyelitis optica (NMO). Methods: To develop an enzyme-linked …

Background Neuromyelitis optica (NMO), a severe demyelinating disease, represents itself
with optic neuritis and longitudinally extensive transverse myelitis. Serum NMO-IgG …

NMO-IgG is a disease-specific autoantibody for neuromyelitis optica (NMO) and its target
antigen is aquaporin-4 (AQP4) water channel. Recently, we established a sensitive anti …

Background Neuromyelitis optica (NMO) is a demyelinating disease of the central nervous
system (CNS) of putative autoimmune aetiology. Early discrimination between multiple …

NMO‐I g G against aquaporin‐4 (AQP 4) is a specific marker for neuromyelitis optica (NMO).
We evaluated the performance of different NMO‐I g G detecting methods. In 124 sera (from …

The current study presents a western blot assay showing good sensitivity (81%) and
specificity (97%) for detecting serum antibodies to Aquaporin-4 (AQP4) in patients with …

Neuromyelitis optica (NMO) is an inflammatory disease that selectively affects the optic
nerves and spinal cord. The discovery of NMO-IgG targeting aquaporin-4 (AQP4) in NMO …

NMO-IgG, a disease-specific autoantibody for neuromyelitis optica, recognizes aquaporin-4
(AQP4) and has been examined by indirect immunofluorescence assay. We developed an …

Abstract Aquaporin‐4 (AQP 4) is a water channel protein that is most highly, but not
exclusively, expressed in the central nervous system. In 2005 AQP 4 was shown to be the …

Background: Neuromyelitis optica (NMO) is a severe inflammatory demyelinating disease
that predominantly affects the optic nerve and spinal cord. Since the discovery of a specific …