This article reports a multidisciplinary approach to produce fluorescently labeled organically
modified silica nanoparticles as a nonviral vector for gene delivery and biophotonics …

Highly fluorescent core–shell silica nanoparticles made by the modified Stöber process (C
dots) are promising as tools for sensing and imaging subcellular agents and structures but …

In this article, a systematic study of the design and development of surface-modification
schemes for silica nanoparticles is presented. The nanoparticle surface design involves an …

The need for novel design strategies for fluorescent nanomaterials to improve our
understanding of biological activities at the molecular level is increasing rapidly. Dye-doped …

We synthesised silica nanoparticles (SiNP) with covalently linked cationic surface
modifications and demonstrated their ability to electrostatically bind, condense and protect …

Diverse polycationic polymers have been used as nonviral transfection agents. Here we
report the ability of colloidal silica particles with covalently attached cationic surface …

The transport of nucleic acid-based reagents is predicated upon developing structurally
stable delivery systems that can preferentially bind and protect DNA and RNA, and release …

In spite of significant advances in early detection and combined treatments, a number of
cancers are often diagnosed at advanced stages and thereby carry a poor prognosis …

We successfully conjugated 1− 2 nm diameter silicon nanoparticles to a 5 '-amino-modified
oligonucleotide (60mer) that contains a C6 linker between amide and phosphate groups …

Silica nanoparticles with embedded fluorescent molecules are used in a variety of
applications requiring the observation of single nanoprobes. We describe a class of …