Autophagy in UV damage response
A Sample, YY He - Photochemistry and photobiology, 2017 - Wiley Online Library
UV radiation exposure from sunlight and artificial tanning beds is the major risk factor for the
development of skin cancer and skin photoaging. UV‐induced skin damage can trigger a …
development of skin cancer and skin photoaging. UV‐induced skin damage can trigger a …
Autophagy: multiple mechanisms to protect skin from ultraviolet radiation‐driven photoaging
M Wang, P Charareh, X Lei… - Oxidative Medicine and …, 2019 - Wiley Online Library
Autophagy is an essential cellular process that maintains balanced cell life. Restriction in
autophagy may induce degenerative changes in humans. Natural or pathological aging of …
autophagy may induce degenerative changes in humans. Natural or pathological aging of …
Autophagy plays an essential role in ultraviolet radiation-driven skin photoaging
J Ma, Y Teng, Y Huang, X Tao, Y Fan - Frontiers in Pharmacology, 2022 - frontiersin.org
Photoaging is characterized by a chronic inflammatory response to UV light. One of the most
prominent features of cutaneous photoaging is wrinkling, which is due primarily to a loss of …
prominent features of cutaneous photoaging is wrinkling, which is due primarily to a loss of …
Pharmacological activation of autophagy restores cellular homeostasis in ultraviolet-(B)-induced skin photodamage
Ultraviolet (UV) exposure to the skin causes photo-damage and acts as the primary
etiological agent in photo-carcinogenesis. UV-B exposure induces cellular damage and is …
etiological agent in photo-carcinogenesis. UV-B exposure induces cellular damage and is …
[HTML][HTML] Autophagy is induced by UVA and promotes removal of oxidized phospholipids and protein aggregates in epidermal keratinocytes
Y Zhao, CF Zhang, H Rossiter, L Eckhart… - Journal of Investigative …, 2013 - Elsevier
The skin is exposed to environmental insults such as UV light that cause oxidative damage
to macromolecules. A centerpiece in the defense against oxidative stress is the Nrf2 (nuclear …
to macromolecules. A centerpiece in the defense against oxidative stress is the Nrf2 (nuclear …
[HTML][HTML] Ultraviolet B radiation down-regulates ULK1 and ATG7 expression and impairs the autophagy response in human keratinocytes
X Chen, L Li, S Xu, W Bu, K Chen, M Li, H Gu - Journal of Photochemistry …, 2018 - Elsevier
Autophagy is a self-digestive pathway that helps to maintain cellular homeostasis, and many
autophagy-related gene (ATG) s involved the regulation of the autophagy process …
autophagy-related gene (ATG) s involved the regulation of the autophagy process …
[HTML][HTML] The role of autophagy in skin fibroblasts, keratinocytes, melanocytes, and epidermal stem cells
D Jeong, NP Qomaladewi, J Lee, SH Park… - Journal of Investigative …, 2020 - Elsevier
Human skin acts as a barrier to protect our bodies from UV rays and external pathogens and
to prevent water loss. Phenotypes of aging, or natural aging due to chronic damage, include …
to prevent water loss. Phenotypes of aging, or natural aging due to chronic damage, include …
Autophagy induction regulates aquaporin 3‐mediated skin fibroblast ageing
H Xie, L Zhou, F Liu, J Long, S Yan… - British Journal of …, 2022 - academic.oup.com
Background Long‐and short‐term ultraviolet (UV) exposure have distinct biological effects
on human fibroblasts. Objectives To elucidate the underlying mechanisms of the biological …
on human fibroblasts. Objectives To elucidate the underlying mechanisms of the biological …
[HTML][HTML] Insights into autophagy machinery in cells related to skin diseases and strategies for therapeutic modulation
Y Wang, X Wen, D Hao, M Zhou, X Li, G He… - Biomedicine & …, 2019 - Elsevier
Autophagy, literally meaning" self-eating," is a highly conserved process that is part of the
eukaryotic cell cycle. Morphologically, the double membrane contains vesicles with …
eukaryotic cell cycle. Morphologically, the double membrane contains vesicles with …
Autophagy: guardian of skin barrier
HJ Kim, J Park, SK Kim, H Park, JE Kim, S Lee - Biomedicines, 2022 - mdpi.com
Autophagy is a major degradation pathway that removes harmful intracellular substances to
maintain homeostasis. Various stressors, such as starvation and oxidative stress, upregulate …
maintain homeostasis. Various stressors, such as starvation and oxidative stress, upregulate …