An elastase-inhibiting, plaque-targeting and neutrophil-hitchhiking liposome against atherosclerosis
Y Shi, M Dong, Y Wu, F Gong, Z Wang, L Xue, Z Su - Acta Biomaterialia, 2024 - Elsevier
Neutrophil extracellular traps (NETs) play a crucial role in the formation of vulnerable
plaques and the development of atherosclerosis. Alleviating the pathological process of …
plaques and the development of atherosclerosis. Alleviating the pathological process of …
Neutrophil membrane biomimetic delivery system (Ptdser‐NM‐Lipo/Fer‐1) designed for targeting atherosclerosis therapy
W Li, C Liu, S Wang, N Liu - IET nanobiotechnology, 2023 - Wiley Online Library
Atherosclerosis is a progressive inflammatory disease characterised by excessive lipid
accumulation and inflammatory cell infiltration and is the basis of most cardiovascular …
accumulation and inflammatory cell infiltration and is the basis of most cardiovascular …
Cellular vehicles based on neutrophils enable targeting of atherosclerosis
Y Xue, Y Wu, Q Wang, L Xue, Z Su… - Molecular …, 2019 - ACS Publications
Given the multiple interactions between neutrophils (NEs) and atherosclerosis (AS), in this
study, we exploited NEs as cellular vehicles loaded with cationic liposomes for actively …
study, we exploited NEs as cellular vehicles loaded with cationic liposomes for actively …
Platelet-derived extracellular vesicles to target plaque inflammation for effective anti-atherosclerotic therapy
Atherosclerosis is a kind of chronic inflammatory diseases characterized by dysfunction of
local immune responses. Here we engineer platelet-derived extracellular vesicles (PEVs) to …
local immune responses. Here we engineer platelet-derived extracellular vesicles (PEVs) to …
Targeted neutrophil-mimetic liposomes promote cardiac repair by adsorbing proinflammatory cytokines and regulating the immune microenvironment
J Chen, Y Song, Q Wang, Q Li, H Tan, J Gao… - Journal of …, 2022 - Springer
Acute myocardial infarction (MI) induces a sterile inflammatory response that may result in
poor cardiac remodeling and dysfunction. Despite the progress in anti-cytokine biologics …
poor cardiac remodeling and dysfunction. Despite the progress in anti-cytokine biologics …
An apoptotic body-biomimic liposome in situ upregulates anti-inflammatory macrophages for stabilization of atherosclerotic plaques
Y Wu, Y Zhang, LL Dai, QQ Wang, LJ Xue, Z Su… - Journal of controlled …, 2019 - Elsevier
The macrophages mediated inflammation participates in every stage of atherosclerosis.
Attenuation of macrophages inflammatory responses by active ingredients in atherosclerotic …
Attenuation of macrophages inflammatory responses by active ingredients in atherosclerotic …
Targeted delivery of platelet membrane modified extracellular vesicles into atherosclerotic plaque to regress atherosclerosis
Atherosclerosis is a major underlying cause of cardiovascular disease. Although certain
success has been achieved in treatment for atherosclerosis, the risk of cardiovascular …
success has been achieved in treatment for atherosclerosis, the risk of cardiovascular …
A Zombie Macrophage‐Based “Trojan horse” Enhances the Effect of Efferocytosis Through Immune Regulation for Atherosclerosis Treatment
Y Yao, H Chen, A Barkat, F Liao, Y Xiao… - Advanced Functional …, 2024 - Wiley Online Library
Various immune cell‐mediated drug delivery systems have been reported for precision
medicine, but the proinflammatory differentiation of immunocyte vehicles can exacerbate …
medicine, but the proinflammatory differentiation of immunocyte vehicles can exacerbate …
Theranostic nanoplatform to target macrophages enables the inhibition of atherosclerosis progression and fluorescence imaging of plaque in ApoE (−/−) mice
Q Wang, Y Wang, S Liu, X Sha, X Song, Y Dai… - Journal of …, 2021 - Springer
Background Rupture of atherosclerotic plaque can cause acute malignant heart and
cerebrovascular events, such as acute coronary heart disease, stroke and so on, which …
cerebrovascular events, such as acute coronary heart disease, stroke and so on, which …
Delivery of negatively charged liposomes into the atherosclerotic plaque of apolipoprotein E-deficient mouse aortic tissue
S Zhaorigetu, C Rodriguez-Aguayo… - Journal of liposome …, 2014 - Taylor & Francis
Liposomes have been used to diagnose and treat cancer and, to a lesser extent,
cardiovascular disease. We previously showed the uptake of anionic liposomes into the …
cardiovascular disease. We previously showed the uptake of anionic liposomes into the …