Though neuroimaging, pathology and pathophysiology suggest a subcortical and deep
cortical involvement in Frontotemporal Lobar Degeneration (FTLD), no studies have …

Objectives: There is currently much interest in biomarkers of disease activity in
frontotemporal lobar degeneration (FTLD). We assessed MRI and behavioral measures of …

Gray matter (GM) lobar atrophy and glucose hypometabolism are well-described hallmarks
of frontotemporal lobar degeneration (FTLD), but the relationships between them are still …

Background: Measurement of volumetric changes with MR might be a useful surrogate
endpoint for clinical trials in frontotemporal lobar degeneration (FTLD). Because there is …

Background Cortical and subcortical microstructural modifications are critical to
understanding the pathogenic changes in frontotemporal lobar degeneration (FTLD) …

Background Structural magnetic resonance imaging (MRI) has been used to investigate the
in vivo pathology of frontotemporal lobar degeneration. However, few neuroimaging studies …

Abstract Background/Aims: Fronto-temporal dementia (FTD) designates a group of relatively
common neurodegenerative disorders. The aim of this study was to characterize the patterns …

A novel method of automated MRI volumetry was used to study regional atrophy and
disease progression in repeated MRI measurements of patients with frontotemporal lobar …

Frontotemporal lobar degeneration (FTLD) encompasses a group of diseases characterized
by neuronal loss and gliosis of the frontal and temporal lobes. Almost all cases of FTLD can …

Frontostriatal circuit mediated cognitive dysfunction has been implicated in frontotemporal
lobar degeneration (FTLD) and may differ across subtypes of FTLD. We manually …