Biomaterial matrices are being developed that mimic the key characteristics of the
extracellular matrix, including presenting adhesion sites and displaying growth factors in the …

Biomaterial matrices must permit tissue growth and maturation for the success of tissue
regeneration strategies. Naturally, this accommodation is achieved via the dynamic …

In the field of tissue engineering and regenerative medicine, hydrogels are used as
biomaterials to support cell attachment and promote tissue regeneration due to their unique …

This article summarizes the recent progress in the design and synthesis of hydrogels as
tissue-engineering scaffolds. Hydrogels are attractive scaffolding materials owing to their …

Hydrogels, due to their unique biocompatibility, flexible methods of synthesis, range of
constituents, and desirable physical characteristics, have been the material of choice for …

Hydrogels have widespread use for cell encapsulation because of their ability to be
processed under relatively mild conditions and to mimic native tissue hydration, mechanics …

BACKGROUND: Traditional materials used as in vitro cell culture substrates are rigid and
flat surfaces that lack the exquisite nano-and micro-scale features of the in vivo extracellular …

The extracellular matrix (ECM) and its mechanical properties play an important role in
regulating the cellular responses that occur during tissue regeneration, wound healing, and …

The past decade has seen a decided move from static and passive biomaterials to
biodegradable, dynamic, and stimuli responsive materials in the laboratory and the clinic …

Cells reside in a complex and dynamic extracellular matrix where they interact with a myriad
of biophysical and biochemical cues that direct their function and regulate tissue …