FAM3C: an emerging biomarker and potential therapeutic target for cancer

Y Zhu, Z Pu, G Wang, Y Li, Y Wang, N Li… - Biomarkers in …, 2021 - Taylor & Francis
FAM3C is a member of the FAM3 family. Recently, overexpression of FAM3C has been
reported in numerous types of cancer, including breast and colon cancer. Increasing …

FAM3B promotes progression of oesophageal carcinoma via regulating the AKT–MDM2–p53 signalling axis and the epithelial‐mesenchymal transition

SL He, WP Wang, YS Yang, EM Li… - Journal of Cellular …, 2019 - Wiley Online Library
FAM3B has been suggested to play important roles in the progression of many cancers,
such as gastric, oral, colon and prostate cancer. However, little is known about the role of …

[HTML][HTML] FAM65A as a novel prognostic biomarker in human tumors reveal by a pan-cancer analysis

W Liang, C Mo, J Wei, W Chen, W Gong, J Shi, X Hou… - Discover Oncology, 2021 - Springer
Background Family with sequence similarity 65 member A (FAM65A), also known as
RIPOR1, is differentially expressed between human tumor and non-tumor tissues in kinds of …

Elevated FAM3C promotes cell epithelial–mesenchymal transition and cell migration in gastric cancer

M Shi, G Duan, S Nie, S Shen, X Zou - OncoTargets and therapy, 2018 - Taylor & Francis
Background Tumor metastasis is an important factor in treatment failure for advanced gastric
cancer. Family with sequence similarity 3 member C (FAM3C) is known to play a critical role …

[HTML][HTML] Pan-cancer and single-cell analysis reveals FAM83D expression as a cancer prognostic biomarker

H Yu, Q Chen, Z Wang, X Qian, Y Pan - Frontiers in genetics, 2022 - frontiersin.org
Background: The family with sequence similarity 83 member D (FAM83D) protein is known
to play a significant role in many human diseases. However, its role in cancer remains …

[HTML][HTML] Prognostic significance of FAM83D gene expression across human cancer types

PJ Walian, B Hang, JH Mao - Oncotarget, 2016 - ncbi.nlm.nih.gov
The family with sequence similarity 83, member D (FAM83D) gene has been proposed as a
new prognostic marker for breast cancer. Here we further evaluate the prognostic …

[HTML][HTML] Overexpression of FAM3C protein as a novel biomarker for epithelial-mesenchymal transition and poor outcome in gastric cancer

S Yin, F Chen, P Ye, G Yang - International Journal of Clinical and …, 2018 - ncbi.nlm.nih.gov
Objective: In recent years, overexpression of FAM3C protein has been proved to contribute
to epithelial to mesenchymal transition (EMT) and correlate with poor prognosis in several …

Upregulation of FAM50A promotes cancer development

MZ Hu, ZZ Dai, HY Ji, AQ Zheng, H Liang, MM Shen… - Medical Oncology, 2023 - Springer
FAM50A encodes a nuclear protein involved in mRNA processing; however, its role in
cancer development remains unclear. Herein, we conducted an integrative pan-cancer …

Pan-cancer analysis of the tumorigenic effect and prognostic diagnostic value of fam111b in human carcinomas

H Wu, C Liang - International Journal of General Medicine, 2023 - Taylor & Francis
Introduction FAM111B (FAM111 trypsin-like peptidase B) gene mutations have been linked
to a hereditary fibrosing poikiloderma disorder known to cause poikiloderma, tendon …

[HTML][HTML] FAM83B mediates EGFR-and RAS-driven oncogenic transformation

R Cipriano, J Graham, KLS Miskimen… - The Journal of …, 2012 - Am Soc Clin Investig
Aberrant regulation of growth signaling is a hallmark of cancer development that often
occurs through the constitutive activation of growth factor receptors or their downstream …