Background Vascular endothelial growth factor (VEGF) has been implicated in
tumorigenesis and metastasis, and it presumably mediates the proliferation of endothelial …

BACKGROUND: The majority of patients with non-small cell lung cancer (NSCLC) are
diagnosed with advanced inoperable disease. While treatment with conventional …

BACKGROUND: Lung cancer is the leading cause of cancer death in the world. The
objective of this study was to investigate the expression of vascular endothelial growth …

Aims—High expression of the angiogenic factor vascular endothelial growth factor (VEGF) in
tumours has been found to be associated with poor prognosis in some studies, but not in …

Purpose Antiangiogenic therapies targeting the vascular endothelial growth factor (VEGF)
pathway have yielded more modest clinical benefit to patients with non–small-cell lung …

The process of angiogenesis is an important factor in tumour development. One of the
principal factors implicated in this process is vascular endothelial growth factor (VEGF) …

Vascular endothelial growth factor (VEGF) is a multifunctional cytokine that increases
microvascular permeability and directly stimulates endothelial cell growth and angiogenesis …

BACKGROUND: Angiogenesis plays an important role in tumorigenesis and has attracted
interest as a potential target in cancer treatment. PATIENTS AND METHODS: We examined …

A robust immunohistochemical (IHC) assay for VEGFR2 was developed to investigate its
utility for patient tailoring in clinical trials. The sensitivity, specificity, and selectivity of the IHC …

Background: Understanding and controlling angiogenesis and lymphangiogenesis could
lead to effective strategies for cancer treatment. The aim of our study was to clarify the …