Nirmatrelvir and risk of hospital admission or death in adults with covid-19: emulation of a randomized target trial using electronic health records
Objective To estimate the effectiveness of nirmatrelvir, compared with no treatment, in
reducing admission to hospital or death at 30 days in people infected with the SARS-CoV-2 …
reducing admission to hospital or death at 30 days in people infected with the SARS-CoV-2 …
Non-randomized evaluation of hospitalization after a prescription for nirmatrelvir/ritonavir versus molnupiravir in high-risk COVID-19 outpatients
K Cowman, A Miller, Y Guo, MH Chang… - Journal of …, 2023 - academic.oup.com
Objectives To assess and compare subsequent hospital admissions within 30 days for
patients after receiving a prescription for either oral nirmatrelvir/ritonavir or oral molnupiravir …
patients after receiving a prescription for either oral nirmatrelvir/ritonavir or oral molnupiravir …
Comparison of effectiveness and safety of nirmatrelvir/ritonavir versus sotrovimab for COVID-19: a systematic review and meta-analysis
Background This study aims to compare the effectiveness and safety of nirmatrelvir/ritonavir
(Paxlovid) and sotrovimab for coronavirus disease 2019 (COVID-19). Methods A search was …
(Paxlovid) and sotrovimab for coronavirus disease 2019 (COVID-19). Methods A search was …
Prevalence of contraindications to nirmatrelvir-ritonavir among hospitalized patients with COVID-19 at risk for progression to severe disease
The availability of outpatient treatment options for COVID-19, such as nirmatrelvir-ritonavir,
remdesivir, molnupiravir, and monoclonal antibodies, raises hopes for reducing COVID-19 …
remdesivir, molnupiravir, and monoclonal antibodies, raises hopes for reducing COVID-19 …
[HTML][HTML] Antiviral drug treatment for nonsevere COVID-19: a systematic review and network meta-analysis
T Pitre, R Van Alstine, G Chick, G Leung, D Mikhail… - Cmaj, 2022 - Can Med Assoc
Background: Randomized trial evidence suggests that some antiviral drugs are effective in
patients with COVID-19. However, the comparative effectiveness of antiviral drugs in …
patients with COVID-19. However, the comparative effectiveness of antiviral drugs in …
Efficacy and safety of nirmatrelvir/ritonavir (Paxlovid) for COVID‐19: a rapid review and meta‐analysis
This study aimed to examine the efficacy and safety of nirmatrelvir/ritonavir (Paxlovid) for
coronavirus disease 2019 (COVID‐19). PubMed, Cochrane Library, Web of Science …
coronavirus disease 2019 (COVID‐19). PubMed, Cochrane Library, Web of Science …
Nirmatrelvir/ritonavir for the treatment of immunocompromised adult patients with early‐stage symptomatic COVID‐19: A real‐life experience
JM Caso, M Fernández‐Ruiz… - Journal of Medical …, 2023 - Wiley Online Library
Regardless of vaccination status, progression to severe coronavirus disease 2019 (COVID‐
19) is still a relevant cause of morbidity among immunocompromised patients. Despite the …
19) is still a relevant cause of morbidity among immunocompromised patients. Despite the …
Identifying Veterans Who Benefit From Nirmatrelvir-Ritonavir: A Target Trial Emulation
L Yan, D Bui, Y Li, N Rajeevan… - Clinical Infectious …, 2024 - academic.oup.com
Background Nirmatrelvir-ritonavir is recommended for persons at risk for severe coronavirus
disease 2019 (COVID-19) but remains underutilized. Information on which eligible groups …
disease 2019 (COVID-19) but remains underutilized. Information on which eligible groups …
Effectiveness of Nirmatrelvir–Ritonavir Against the Development of Post–COVID-19 Conditions Among US Veterans: A Target Trial Emulation
GN Ioannou, K Berry, N Rajeevan, Y Li… - Annals of internal …, 2023 - acpjournals.org
Background: COVID-19 has been linked to the development of many post–COVID-19
conditions (PCCs) after acute infection. Limited information is available on the effectiveness …
conditions (PCCs) after acute infection. Limited information is available on the effectiveness …
Oral Molnupiravir and Nirmatrelvir/Ritonavir for the Treatment of COVID-19: A Literature Review with a Focus on Real-World Evidence
I Karniadakis, N Mazonakis, C Tsioutis… - Infectious Disease …, 2023 - mdpi.com
Vaccines remain the cornerstone of medical prevention and are highly effective in reducing
the risk of severe disease and death due to coronavirus disease 2019 (COVID-19). In the …
the risk of severe disease and death due to coronavirus disease 2019 (COVID-19). In the …