Emodin is a natural bioactive compound from traditional Chinese herbs that exerts anti-
inflammatory, antioxidant, anticancer, hepatoprotective, and neuroprotective effects …

Acetaminophen (APAP) is the most commonly used analgesic and antipyretic drug in the
world. However, hepatotoxicity caused by APAP overdose is the most frequent cause of …

Background: Drug-induced liver injury (DILI), represented by acetaminophen (APAP), is a
common cause of acute liver failure in clinics. Paeoniflorin (PF) has been proven to …

Acetaminophen (APAP) overdose can induce acute liver injury (ALI) with significant
morbidity and mortality. Propacetamol is an APAP prodrug, which is clinically bioequivalent …

Background: Acetaminophen (APAP) overdose results in the production of reactive oxygen
species (ROS), induces hepatocyte necrosis, and leads to acute liver failure. Atractylenolide …

Acetaminophen (APAP) is mainly eliminated at a therapeutic dose through glucuronidation
and sulfatation and a small fraction is oxidized by cytochromes P450 (CYP) 2E1, 3A4, and …

Acetaminophen (APAP) is a well-known antipyretic and analgesic drug. However, the
accidental or intentional APAP overdose will induce liver injury and even acute liver failure …

Acetaminophen (APAP) overdose leads to severe hepatotoxicity. Osthole, a natural
coumarin found in traditional Chinese medicinal herbs, has therapeutic potential in the …

Acetaminophen (APAP) overdose causes hepatocytes necrosis and acute liver failure.
Baicalin (BA), a major flavonoid of Scutellariae radix, has potent hepatoprotective properties …

Abstract Background Cirsii Japonici Herba Carbonisata (Dajitan in Chinese) has been used
to treat liver disorders in Asian countries. Pectolinarigenin (PEC), an abundant constituent in …