[HTML][HTML] The human papillomavirus type 11 E1^ E4 protein is not essential for viral genome amplification
L Fang, LR Budgeon, J Doorbar, ER Briggs, MK Howett - Virology, 2006 - Elsevier
An abundant human papillomavirus (HPV) protein E1^ E4 is expressed late in the virus life
cycle in the terminally differentiated layers of epithelia. The expression of E1^ E4 usually …
cycle in the terminally differentiated layers of epithelia. The expression of E1^ E4 usually …
Regulation of human papillomavirus type 16 E7 activity through direct protein interaction with the E2 transcriptional activator
N Gammoh, HS Grm, P Massimi, L Banks - Journal of virology, 2006 - Am Soc Microbiol
In order to ensure a productive life cycle, human papillomaviruses (HPVs) require fine
regulation of their gene products. Uncontrolled activity of the viral oncoproteins E6 and E7 …
regulation of their gene products. Uncontrolled activity of the viral oncoproteins E6 and E7 …
Human papillomavirus type 31 replication modes during the early phases of the viral life cycle depend on transcriptional and posttranscriptional regulation of E1 and …
WG Hubert, LA Laimins - Journal of virology, 2002 - Am Soc Microbiol
The E1 and E2 proteins are both required for papillomavirus DNA replication, and
replication efficiency is controlled by the abundance of these factors. In human …
replication efficiency is controlled by the abundance of these factors. In human …
[HTML][HTML] An acidic amphipathic helix in the bovine papillomavirus E2 protein is critical for DNA replication and interaction with the E1 protein
MK Baxter, AA McBride - Virology, 2005 - Elsevier
The papillomavirus E2 proteins function in viral transcriptional regulation, and genome
replication and episomal maintenance. The transactivation domain is essential for these …
replication and episomal maintenance. The transactivation domain is essential for these …
Control of viral replication and transcription by the papillomavirus E8^ E2 protein
M Dreer, S Van De Poel, F Stubenrauch - Virus research, 2017 - Elsevier
Human papillomaviruses have adjusted their replication levels to the differentiation state of
the infected keratinocyte. PV genomes replicate in undifferentiated cells at low levels and to …
the infected keratinocyte. PV genomes replicate in undifferentiated cells at low levels and to …
Dimerization of the human papillomavirus type 16 E2 N terminus results in DNA looping within the upstream regulatory region
EE Hernandez-Ramon, JE Burns, W Zhang… - Journal of …, 2008 - Am Soc Microbiol
Papillomavirus E2 proteins play a central role in regulating viral gene expression and
replication. DNA-binding activity is associated with the C-terminal domain of E2, which forms …
replication. DNA-binding activity is associated with the C-terminal domain of E2, which forms …
A papillomavirus E2 phosphorylation mutant exhibits normal transient replication and transcription but is defective in transformation and plasmid retention
CW Lehman, DS King, MR Botchan - Journal of virology, 1997 - Am Soc Microbiol
Papillomavirus DNA persists in infected cells as a nuclear plasmid, causing epithelial
lesions in many hosts, including humans. The viral protein E2 is required for both replication …
lesions in many hosts, including humans. The viral protein E2 is required for both replication …
The E8∧E2 Gene Product of Human Papillomavirus Type 16 Represses Early Transcription and Replication but Is Dispensable for Viral Plasmid Persistence in …
MJ Lace, JR Anson, GS Thomas, LP Turek… - Journal of …, 2008 - Am Soc Microbiol
ABSTRACT A conserved E8∧ E2 spliced mRNA is detected in keratinocytes transfected
with human papillomavirus type 16 (HPV-16) plasmid DNA. Expression of HPV-16 E8∧ E2 …
with human papillomavirus type 16 (HPV-16) plasmid DNA. Expression of HPV-16 E8∧ E2 …
The Interaction between Human Papillomavirus Type 16 El and E2 Proteins is Blocked by An Antibody to the N‐Terminal Region of E2
MH Hibma, K Raj, SJ Ely, M Stanley… - European journal of …, 1995 - Wiley Online Library
Replication of papillomavirus DNA requires two virally encoded proteins, El and E2. We
expressed human papillomavirus (HPV) type 16 El and E2 in bacteria and showed that …
expressed human papillomavirus (HPV) type 16 El and E2 in bacteria and showed that …
[HTML][HTML] The role of the human papillomavirus type 18 E7 oncoprotein during the complete viral life cycle
ME McLaughlin-Drubin, JL Bromberg-White, C Meyers - Virology, 2005 - Elsevier
The role of the human papillomavirus oncoprotein E7 in carcinogenesis has been
extensively studied. While the role of HPV E7 in the viral life cycle has also been studied …
extensively studied. While the role of HPV E7 in the viral life cycle has also been studied …