[HTML][HTML] The interleukin-1 cytokine family members: Role in cancer pathogenesis and potential therapeutic applications in cancer immunotherapy
Abstract The interleukin-1 (IL-1) family is one of the first described cytokine families and
consists of eight cytokines (IL-1β, IL-1α, IL-18, IL-33, IL-36α, IL-36β, IL-36γ and IL-37) and …
consists of eight cytokines (IL-1β, IL-1α, IL-18, IL-33, IL-36α, IL-36β, IL-36γ and IL-37) and …
IL-6 and related cytokines as the critical lynchpins between inflammation and cancer
K Taniguchi, M Karin - Seminars in immunology, 2014 - Elsevier
Inflammatory responses play pivotal roles in cancer development, including tumor initiation,
promotion, progression, and metastasis. Cytokines are now recognized as important …
promotion, progression, and metastasis. Cytokines are now recognized as important …
[HTML][HTML] IL-1 family members in cancer; two sides to every story
The IL-1 family of cytokines currently comprises of seven ligands with pro-inflammatory
activity (IL-1α and IL-1β, IL-18, IL-33, IL-36α, IL-36β, IL-36γ) as well as two ligands with anti …
activity (IL-1α and IL-1β, IL-18, IL-33, IL-36α, IL-36β, IL-36γ) as well as two ligands with anti …
Gene of the month: Interleukin 6 (IL-6)
P Ataie-Kachoie, MH Pourgholami… - Journal of clinical …, 2014 - jcp.bmj.com
The Interleukin 6 (IL-6) gene encodes the classic proinflammatory cytokine IL-6. It is also
known as interferon-β2 (IFN-β2), B cell stimulatory factor-2 and hybridoma/plasmacytoma …
known as interferon-β2 (IFN-β2), B cell stimulatory factor-2 and hybridoma/plasmacytoma …
The interleukin (IL)-1 cytokine family–Balance between agonists and antagonists in inflammatory diseases
Abstract The interleukin (IL)-1 family of cytokines comprises 11 members, including 7 pro-
inflammatory agonists (IL-1α, IL-1β, IL-18, IL-33, IL-36α, IL-36β, IL-36γ) and 4 defined or …
inflammatory agonists (IL-1α, IL-1β, IL-18, IL-33, IL-36α, IL-36β, IL-36γ) and 4 defined or …
The IL-1 family in tumorigenesis and antitumor immunity
The IL-1 family of cytokines consists of IL-1α, IL-1β, IL-18, IL-33, IL-36α, IL-36β, and IL-36γ.
These proteins form four signaling receptor complexes: the IL-1 receptor (IL-1R1 and IL …
These proteins form four signaling receptor complexes: the IL-1 receptor (IL-1R1 and IL …
The IL-2 cytokine family in cancer immunotherapy
GC Sim, L Radvanyi - Cytokine & growth factor reviews, 2014 - Elsevier
The use of cytokines from the IL-2 family (also called the common γ chain cytokine family)
such as interleukin (IL)-2, IL-7, IL-15, and IL-21 to activate the immune system of cancer …
such as interleukin (IL)-2, IL-7, IL-15, and IL-21 to activate the immune system of cancer …
The role of the interleukin (IL)-6/IL-6 receptor axis in cancer
Interleukin-6 (IL-6) is a pleiotropic cytokine that activates a classic signalling pathway upon
binding to its membrane-bound receptor (IL-6R). Alternatively, IL-6 may 'trans-signal'in a …
binding to its membrane-bound receptor (IL-6R). Alternatively, IL-6 may 'trans-signal'in a …
[HTML][HTML] Interleukin-6 cytokine: a multifunctional glycoprotein for cancer
P Zarogoulidis, L Yarmus, K Darwiche… - Immunome …, 2013 - ncbi.nlm.nih.gov
Interleukin 6 is a multifunctional cytokine. Its increased levels have been associated with
elevated cancer risk, and also these levels have been found to be a prognostic factor for …
elevated cancer risk, and also these levels have been found to be a prognostic factor for …
Recent insights into targeting the IL-6 cytokine family in inflammatory diseases and cancer
SA Jones, BJ Jenkins - Nature reviews immunology, 2018 - nature.com
The IL-6 family of cytokines consists of IL-6, IL-11, IL-27, IL-31, oncostatin M (OSM),
leukaemia inhibitory factor (LIF), ciliary neurotrophic factor (CNTF), cardiotrophin 1 (CT-1) …
leukaemia inhibitory factor (LIF), ciliary neurotrophic factor (CNTF), cardiotrophin 1 (CT-1) …