Breast cancer (BC) is the most commonly diagnosed cancer in women. The PI3K/AKT/mTOR
pathway is among the most frequently dysregulated pathways in patients with BC. The …

Breast cancer is the cancer with the highest prevalence in women and is the number‐one
cause of cancer mortality worldwide. Cell transduction is a fundamental process in the …

The PI3K/Akt/mTOR signaling pathway is involved in the inhibition of tumor cell apoptosis,
the promotion of cell survival, cell cycle regulation, tumor angiogenesis, invasion, and …

Simple Summary PI3K signaling pathway plays an essential role in many cellular processes
and is frequently altered in breast cancer, leading to increased tumor growth and reduced …

Abstract The PI3K/Akt/mTOR pathway plays a role in various oncogenic processes in breast
cancer and key pathway aberrations have been identified which drive the different molecular …

Background: The most recurrent and considered second most frequent cause of cancer-
related deaths worldwide in women is the breast cancer. The key to diagnosis is early …

Breast cancer (BC) is the most common women cancer and second most common cause of
cancer death in women. A woman living in the United States has 12.3% lifetime risk of being …

The phosphoinositide 3 kinase (PI3K)/Akt/mammalian (or mechanistic) target of rapamycin
(mTOR) pathway is a complicated intracellular pathway, which leads to cell growth and …

3511 Background: The PI3K/Akt/mTOR pathway is found dysregulated in multiple tumours,
including breast cancer (BC). RAD001 is a recently developed drug which blocks mTOR. To …

Aberrant activation of the PI3K/Akt/mTOR pathway is found in many types of cancer and thus
plays a major role in breast cancer cell proliferation and anti-cancer drug resistance. The …