Defective zonae pellucidae in Zp2-null mice disrupt folliculogenesis, fertility and development

TL Rankin, M O'Brien, E Lee, K Wigglesworth… - …, 2001 - journals.biologists.com
All vertebrate eggs are surrounded by an extracellular matrix. This matrix is known as the
zona pellucida in mammals and is critically important for the survival of growing oocytes …

Abnormal zonae pellucidae in mice lacking ZP1 result in early embryonic loss

T Rankin, P Talbot, E Lee, J Dean - Development, 1999 - journals.biologists.com
All vertebrates have an egg shell that surrounds ovulated eggs and plays critical roles in
gamete recognition. This extracellular matrix is known as the zona pellucida in eutherian …

Mice homozygous for an insertional mutation in the Zp3 gene lack a zona pellucida and are infertile

T Rankin, M Familari, E Lee, A Ginsberg… - …, 1996 - journals.biologists.com
Mammalian oocytes synthesize and secrete a zona pellucida that surrounds the growing
oocytes, ovulated eggs and preimplantation embryos. The extracellular zona matrix is …

The mouse zona pellucida: folliculogenesis, fertility and pre-implantation development

T Rankin, S Soyal, J Dean - Molecular and cellular endocrinology, 2000 - Elsevier
Perinatally, oocytes within the mouse ovary become surrounded by a layer of flattened
granulosa cells and form primordial follicles. The subsequent accretion of the zona pellucida …

Zona pellucida genes and proteins: Essential players in mammalian oogenesis and fertility

PM Wassarman, ES Litscher - Genes, 2021 - mdpi.com
All mammalian oocytes and eggs are surrounded by a relatively thick extracellular matrix
(ECM), the zona pellucida (ZP), that plays vital roles during oogenesis, fertilization, and …

The zona pellucida: using molecular genetics to study the mammalian egg coat

T Rankin, J Dean - Reviews of Reproduction, 2000 - rep.bioscientifica.com
An extracellular matrix that mediates critical steps in fertilization and early development
surrounds all vertebrate eggs. In mice and humans, this matrix is known as the zona …

Mouse zona pellucida genes and glycoproteins

PM Wassarman, L Jovine, ES Litscher - Cytogenetic and Genome …, 2004 - karger.com
The zona pellucida (ZP) is a thick extracellular coat that surrounds all mammalian eggs. The
ZP plays important roles during oogenesis, fertilization, and preimplantation development …

The mouse egg's zona pellucida

PM Wassarman, ES Litscher - Current topics in developmental biology, 2018 - Elsevier
All mammalian eggs are surrounded by a highly specialized extracellular matrix (ECM),
called the zona pellucida (ZP), that functions before, during, and after fertilization. Unlike …

Oocyte-Specific Expression of Mouse Zp-2: Developmental Regulation of the Zona Pellucida Genes

LF Liang, SM Chamow, J Dean - Molecular and Cellular Biology, 1990 - Taylor & Francis
The zona pellucida surrounds all mammalian oocytes and plays a vital role at fertilization
and in early development. The genes that code for two of the mouse zona proteins (ZP2 and …

Human ZP3 restores fertility in Zp3 null mice without affecting order-specific sperm binding

TL Rankin, ZB Tong, PE Castle, E Lee… - …, 1998 - journals.biologists.com
The mammalian zona pellucida surrounding ovulated eggs mediates sperm binding at
fertilization, provides a postfertilization block to polyspermy, and facilitates passage of pre …