Phospholipid scramblase 1 potentiates the antiviral activity of interferon

B Dong, Q Zhou, J Zhao, A Zhou, RN Harty… - Journal of …, 2004 - Am Soc Microbiol
ABSTRACT Phospholipid scramblase 1 (PLSCR1) is an interferon (IFN)-and growth factor-
inducible, calcium-binding protein that either inserts into the plasma membrane or binds …

[HTML][HTML] Phospholipid scramblase 1 binds to the promoter region of the inositol 1, 4, 5-triphosphate receptor type 1 gene to enhance its expression

Q Zhou, I Ben-Efraim, JL Bigcas, D Junqueira… - Journal of Biological …, 2005 - ASBMB
Phospholipid scramblase 1 (PLSCR1) is a multiply palmitoylated, endofacial membrane
protein originally identified based on its capacity to promote accelerated transbilayer …

[HTML][HTML] Interferon-α-induced expression of phospholipid scramblase 1 through STAT1 requires the sequential activation of protein kinase Cδ and JNK

KW Zhao, D Li, Q Zhao, Y Huang, RH Silverman… - Journal of Biological …, 2005 - ASBMB
Phospholipid scramblase 1 (PLSCR1), a calcium-binding protein that either inserts into the
plasma membrane or binds to genomic DNA in the nucleus, has been shown to contribute to …

Transcriptional control of the human plasma membranephospholipid scramblase 1 gene is mediated by interferon-α

Q Zhou, J Zhao, F Al-Zoghaibi, A Zhou… - Blood, The Journal …, 2000 - ashpublications.org
Interferons (IFNs) mediate their diverse biologic activities through induction of the
expression of multiple genes. Whereas the mode of action of certain of these IFN-regulated …

Palmitoylation of phospholipid scramblase 1 controls its distribution between nucleus and plasma membrane

T Wiedmer, J Zhao, M Nanjundan, PJ Sims - Biochemistry, 2003 - ACS Publications
Phospholipid scramblase 1 (PLSCR1) is a Ca2+-binding, endofacial plasma membrane
protein thought to contribute to the transbilayer movement of phosphatidylserine and other …

[HTML][HTML] Phospholipid scramblase 1: a protein with multiple functions via multiple molecular interactors

J Dal Col, MJ Lamberti, A Nigro, V Casolaro… - Cell Communication and …, 2022 - Springer
Abstract Phospholipid scramblase 1 (PLSCR1) is the most studied protein of the scramblase
family. Originally, it was identified as a membrane protein involved in maintaining plasma …

Inhibition of Hepatitis B virus replication by phospholipid scramblase 1 in vitro and in vivo

J Yang, X Zhu, J Liu, X Ding, M Han, W Hu, X Wang… - Antiviral research, 2012 - Elsevier
Human Phospholipid scramblase 1 (PLSCR1) is an α/β interferon-inducible protein that
mediates antiviral activity against RNA viruses including vesicular stomatitis virus (VSV) and …

Phospholipid scramblases: an overview

SK Sahu, SN Gummadi, N Manoj… - Archives of biochemistry …, 2007 - Elsevier
Phospholipid scramblases are a group of homologous proteins that are conserved in all
eukaryotic organisms. They are believed to be involved in destroying plasma membrane …

[HTML][HTML] Plasma membrane phospholipid scramblase 1 promotes EGF-dependent activation of c-Src through the epidermal growth factor receptor

M Nanjundan, J Sun, J Zhao, Q Zhou, PJ Sims… - Journal of Biological …, 2003 - ASBMB
Phospholipid scramblase (PLSCR1) is a multiply palmitoylated, calcium-binding endofacial
membrane protein proposed to mediate transbilayer movement of plasma membrane …

Phospholipid Scramblase 1 Is Imported into the Nucleus by a Receptor-Mediated Pathway and Interacts with DNA,

I Ben-Efraim, Q Zhou, T Wiedmer, L Gerace… - Biochemistry, 2004 - ACS Publications
Phospholipid scramblase 1 (PLSCR1) is a multiply palmitoylated, Ca2+-binding, endofacial
plasma membrane protein originally identified by its capacity to accelerate transbilayer …