Engineering of exosomes to target cancer metastasis

Z Zhang, JA Dombroski, MR King - Cellular and Molecular Bioengineering, 2020 - Springer
As a nanoscale subset of extracellular vehicles, exosomes represent a new pathway of
intercellular communication by delivering cargos such as proteins and nucleic acids to …

Exosomes: cell-derived nanoplatforms for the delivery of cancer therapeutics

H Kim, EH Kim, G Kwak, SG Chi, SH Kim… - International journal of …, 2020 - mdpi.com
Exosomes are cell-secreted nanovesicles that naturally contain biomolecular cargoes such
as lipids, proteins, and nucleic acids. Exosomes mediate intercellular communication …

Engineered exosomes for tumor-targeted drug delivery: a focus on genetic and chemical functionalization

A Akbari, F Nazari-Khanamiri, M Ahmadi, M Shoaran… - Pharmaceutics, 2022 - mdpi.com
Cancer is the main cause of death worldwide. The limitations in traditional cancer therapies
provoked the advance and use of several nanotechnologies for more effective and nontoxic …

Engineered exosomes: a promising vehicle in cancer therapy

F Pooresmaeil, S Andi, B Hasannejad-Asl… - Therapeutic …, 2023 - Taylor & Francis
During the past few decades, researchers have attempted to discover an effective treatment
for cancer. Exosomes are natural nanovesicles released by various cells and play a role in …

Exosome as a delivery vehicle for cancer therapy

B Moon, S Chang - Cells, 2022 - mdpi.com
Exosomes are small extracellular vesicles that are naturally produced and carry
biomolecules such as proteins, microRNAs, and metabolites. Because of their small size …

[HTML][HTML] Engineered exosomes for cancer theranostics: Next-generation tumor targeting

VP Chavda, VV Sugandhi, CV Pardeshi, RJ Patil… - Journal of Drug Delivery …, 2023 - Elsevier
Exosomes are multivesicular bodies of which the plasma membrane fuse to release the
caring moiety into the surrounding body fluids. They are best known for their function in …

Recent advances in exosome-based drug delivery for cancer therapy

H Kim, H Jang, H Cho, J Choi, KY Hwang, Y Choi… - Cancers, 2021 - mdpi.com
Simple Summary Exosomes derived from various sources can deliver therapeutic agents
such as small molecule drugs, nucleic acids, and proteins to cancer cells by passive or …

Engineering exosomes for cancer therapy

KE Gilligan, RM Dwyer - International journal of molecular sciences, 2017 - mdpi.com
There remains an urgent need for novel therapeutic strategies to treat metastatic cancer,
which results in over 8 million deaths annually worldwide. Following secretion, exosomes …

[HTML][HTML] Engineering exosomes for targeted drug delivery

Y Liang, L Duan, J Lu, J Xia - Theranostics, 2021 - ncbi.nlm.nih.gov
Exosomes are cell-derived nanovesicles that are involved in the intercellular transportation
of materials. Therapeutics, such as small molecules or nucleic acid drugs, can be …

Clinical implications of exosomes: targeted drug delivery for cancer treatment

AE Massey, S Malik, M Sikander, KA Doxtater… - International Journal of …, 2021 - mdpi.com
Exosomes are nanoscale vesicles generated by cells for intercellular communication. Due to
their composition, significant research has been conducted to transform these particles into …