Drug delivery to the retina is a challenging task owing to its complex physiology and
presence of the blood-retinal barrier (BRB), which regulates the permeation of substances …

The previous in vivo study revealed the carrier-mediated transport of riboflavin (vitamin B 2)
across the blood-retinal barrier (BRB). In the present study, the blood-to-retina supply of …

Purpose: To investigate the functional expression of a carrier-mediated transport mechanism
for riboflavin (vitamin B 2) across cultured rabbit primary corneal epithelial cells (rPCECs) …

Riboflavin is an important water soluble vitamin (B2) required for metabolic reactions,
normal cellular growth, differentiation and function. Mammalian brain cells cannot …

Riboflavin (vitamin B 2) supply to the retina across the inner blood-retinal barrier (BRB) was
investigated. In rats, the apparent influx permeability clearance of [3 H] riboflavin (62.8 …

In mammalian cells (including those of the ocular system), the water‐soluble vitamin B2
(riboflavin, RF) assumes an essential role in a variety of metabolic reactions and is critical for …

The role of riboflavin in cell maintenance and growth, and the mechanism by which it is
absorbed into various human tissues and cell lines has been extensively studied over the …

The retention and cellular internalization of drug delivery systems and theranostics for
cancer therapy can be improved by targeting molecules. Since an increased uptake of …

The primary objective of this study was to investigate the expression of a specialized carrier-
mediated system for folic acid and to delineate its uptake mechanism and intracellular …

Introduction: The blood-retinal barrier (BRB) is the barrier separating the blood and neural
retina, and transport systems for low-weight molecules at the BRB are expected to be useful …