Hydrogel Applications in the Diagnosis and Treatment of Glioblastoma

S Zhang, R Zhong, MR Younis, H He… - … Applied Materials & …, 2024 - ACS Publications
Glioblastoma multiforme (GBM), a common malignant neurological tumor, has boundaries
indistinguishable from those of normal tissue, making complete surgical removal ineffective …

The role of hydrogels in the management of brain tumours: a narrative review

Z Anas, SFS Hasan, MA Moiz… - Annals of Medicine …, 2024 - journals.lww.com
Conventional therapeutic techniques for brain tumours have limitations and side effects,
necessitating the need for alternative treatment options. MRI-monitored therapeutic hydrogel …

Hydrogel-based drug delivery nanosystems for the treatment of brain tumors

J Basso, A Miranda, S Nunes, T Cova, J Sousa… - Gels, 2018 - mdpi.com
Chemotherapy is commonly associated with limited effectiveness and unwanted side effects
in normal cells and tissues, due to the lack of specificity of therapeutic agents to cancer cells …

Advances in Hydrogels of Drug Delivery Systems for the Local Treatment of Brain Tumors

J Yang, Z Wang, C Ma, H Tang, H Hao, M Li, X Luo… - Gels, 2024 - mdpi.com
The management of brain tumors presents numerous challenges, despite the employment of
multimodal therapies including surgical intervention, radiotherapy, chemotherapy, and …

Anticancer drug-loaded hydrogels as drug delivery systems for the local treatment of glioblastoma

C Bastiancich, P Danhier, V Préat, F Danhier - Journal of Controlled …, 2016 - Elsevier
Among central nervous system tumors, Glioblastoma (GBM) is the most common, aggressive
and neurological destructive primary brain tumor in adults. Standard care therapy for GBM …

Hydrogel on a smart nanomaterial interface to carry therapeutics for digitalized glioma treatment

X Zhao, B Javed, F Tian, K Liu - Gels, 2022 - mdpi.com
Glioma is considered the primary brain tumor to cause brain illnesses, and it is difficult to
treat and shows resistance to various routine therapeutics. The most common treatments to …

Glioblastoma behaviors in three-dimensional collagen-hyaluronan composite hydrogels

SS Rao, J DeJesus, AR Short, JJ Otero… - … Applied Materials & …, 2013 - ACS Publications
Glioblastoma multiforme (GBM) tumors, which arise from glia in the central nervous system
(CNS), are one of the most deadly forms of human cancer with a median survival time of∼ 1 …

A Big Prospect for Hydrogel Nano-System in Glioma

L Zhang, F Teng, H Xin, W Xu, W Wu… - International Journal of …, 2024 - Taylor & Francis
Patients diagnosed with glioma typically face a limited life expectancy (around 15 months on
average), a bleak prognosis, and a high likelihood of recurrence. As such, glioma is …

Characterization and structure-property relationships of an injectable thiol-Michael addition hydrogel toward compatibility with glioblastoma therapy

ZM Khan, E Wilts, E Vlaisavljevich, TE Long… - Acta Biomaterialia, 2022 - Elsevier
Glioblastoma multiforme (GBM) is an aggressive primary brain cancer and although patients
undergo surgery and chemoradiotherapy, residual cancer cells still migrate to healthy brain …

A comparative study of brain tumor cells from different age and anatomical locations using 3D biomimetic hydrogels

C Wang, S Sinha, X Jiang, S Fitch, C Wilson, V Caretti… - Acta biomaterialia, 2020 - Elsevier
Brain tumors exhibit vast genotypic and phenotypic diversity depending on patient age and
anatomical location. Hydrogels hold great promise as 3D in vitro models for studying brain …