Role of cell‐to‐cell communication in cancer: New features, insights, and directions

EA Eugenin - Cancer Reports, 2019 - Wiley Online Library
The current special issue entitled “Role of tunneling nanotubes (TNTs) in carcinogenesis”
was designed to discuss the role of cell‐to‐cell communication, especially TNTs, in cancer …

Tunneling nanotubes: Intercellular conduits for direct cell-to-cell communication in cancer

E Lou, S Subramanian - Intercellular Communication in Cancer, 2015 - Springer
Tunneling nanotubes (TNTs) are actin-based cytoplasmic extensions that directly transfer
cellular cargo between connected cells. Intercellular transport of signaling molecules and …

Cellular and molecular networking within the ecosystem of cancer cell communication via tunneling nanotubes

E Lou, E Zhai, A Sarkari, S Desir, P Wong… - Frontiers in cell and …, 2018 - frontiersin.org
Intercellular communication is vital to the ecosystem of cancer cell organization and
invasion. Identification of key cellular cargo and their varied modes of transport are important …

Tunneling nanotubes: The intercellular conduits contributing to cancer pathogenesis and its therapy

PK Melwani, BN Pandey - Biochimica et Biophysica Acta (BBA)-Reviews …, 2023 - Elsevier
Tunneling nanotubes (TNTs) are intercellular conduits, which meet the communication
needs of non-adjacent cells situated in the same tissue but at distances up to a few hundred …

Tunneling nanotubes, a novel mode of tumor cell–macrophage communication in tumor cell invasion

SJ Hanna, K McCoy-Simandle, E Leung… - Journal of cell …, 2019 - journals.biologists.com
The interaction between tumor cells and macrophages is crucial in promoting tumor invasion
and metastasis. In this study, we examined a novel mechanism of intercellular …

Tunneling nanotubes: the fuel of tumor progression?

G Pinto, C Brou, C Zurzolo - Trends in cancer, 2020 - cell.com
Tunneling nanotubes (TNTs) are thin membrane tubes connecting remote cells and allowing
the transfer of cellular content. TNTs have been reported in several cancer in vitro, ex vivo …

[HTML][HTML] Control of long-distance cell-to-cell communication and autophagosome transfer in squamous cell carcinoma via tunneling nanotubes

I Sáenz-de-Santa-María, C Bernardo-Castiñeira… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Tunneling nanotubes (TnTs) are thin channels that temporally connect nearby cells allowing
the cell-to-cell trafficking of biomolecules and organelles. The presence or absence of TnTs …

Tunneling Nanotubes: A new paradigm for studying intercellular communication and therapeutics in cancer

E Lou, S Fujisawa, A Barlas, Y Romin… - … & integrative biology, 2012 - Taylor & Francis
Tunneling nanotubes are actin-based cytoplasmic extensions that function as intercellular
channels in a wide variety of cell types. There is a renewed and keen interest in the …

A Ticket to Ride: The Implications of Direct Intercellular Communication via Tunneling Nanotubes in Peritoneal and Other Invasive Malignancies

E Lou - Frontiers in Oncology, 2020 - frontiersin.org
It is well established that the role of the tumor microenvironment (TME) in cancer
progression and therapeutic resistance is crucial, but many of the underlying mechanisms …

Specialized intercellular communications via tunnelling nanotubes in acute and chronic leukemia

A Allegra, M Di Gioacchino, G Cancemi, M Casciaro… - Cancers, 2022 - mdpi.com
Simple Summary Tunneling nanotubes (TNTs) are cytoplasmic channels which regulate the
contacts between cells and allow the transfer of several elements, including ions …