Since first being described in the fruit fly Drosophila melanogaster, Toll-like receptors (TLRs)
have proven to be of great interest to immunologists and investigators interested in the …

Inflammation is set off when innate immune cells detect infection or tissue injury. Tight
control of the severity, duration, and location of inflammation is an absolute requirement for …

ABSTRACT Toll-like receptor 3 (TLR3) is a pattern recognition receptor that senses
exogenous (viral) as well as endogenous (mammalian) double-stranded RNA in …

Toll-like receptors (TLRs) are the pattern recognition receptors, which are activated by
foreign and host molecules in order to initiate the immune response. They play a crucial role …

Innate immune cells have a critical role in defense against infection and disease. Central to
this is the broad specificity with which they can detect pathogen‐associated patterns and …

The immune system is a very diverse system of the host that evolved during evolution to
cope with various pathogens present in the vicinity of environmental surroundings inhabited …

Roles for Toll-like receptors (TLRs) are emerging in conditions such as sepsis syndrome,
systemic lupus erythromatosis, rheumatoid arthritis and asthma, suggesting that the …

Toll-like receptors (TLRs) are prototypic pattern recognition receptors (PRRs) best known for
their ability to activate the innate immune system in response to conserved microbial …

The health of living organisms is constantly challenged by bacterial and viral threats. The
recognition of pathogenic microorganisms by diverse receptors triggers a variety of host …

Toll-like receptors (TLRs) play a crucial role in host defence and inflammation. Given that a
significant amount of evidence implicates TLRs in the pathogenesis of immune diseases …