Background The utility of kidney organoids in regenerative medicine will rely on the
functionality of the glomerular and tubular structures in these tissues. Recent studies have …

Background Kidney cancer is one of the most common solid tumors. The advancement of
human kidney cancer research and treatment has been hindered by a lack of research …

Here we describe a novel method in which embryonic kidneys are dissociated into single-
cell suspensions and then reaggregated to form organotypic renal structures. Kidney cell …

Human pluripotent stem cell (hPSC)-derived kidney organoids may facilitate disease
modeling and the generation of tissue for renal replacement. Long-term application …

Background Human kidney organoids hold promise for studying development, disease
modelling and drug screening. However, the utility of stem cell-derived kidney tissues will …

During development, distinct progenitors contribute to the nephrons versus the ureteric
epithelium of the kidney. Indeed, previous human pluripotent stem-cell-derived models of …

Recent technical advances in the stem cell field have enabled the in vitro generation of
complex structures resembling whole organs termed organoids. Most of these approaches …

Human induced pluripotent stem cell-derived kidney organoids have potential for disease
modeling and to be developed into clinically transplantable auxiliary tissue. However, they …

Kidney organoids derived from human pluripotent stem cells have great utility for
investigating organogenesis and disease mechanisms and, potentially, as a replacement …

Kidney organoids derived from the human pluripotent stem cells (hPSCs) recapitulating
human kidney are the attractive tool for kidney regeneration, disease modeling, and drug …