The protective effects of ilexsaponin A on ischemia-reperfusion-induced myocardial injury
were investigated. Myocardial ischemia/reperfusion model was established in male Sprague …

Doxorubicin (Dox) is an anthracycline antibiotic for cancer therapy with limited usage due to
cardiotoxicity. Isorhamnetin is a nature antioxidant with obvious cardiac protective effect. The …

Doxorubicin (DOX) is a potent anthracycline antineoplastic drug. However, its dose-
dependent cardiotoxicity limits its clinical application. Ononin is a natural isoflavone …

Doxorubicin as anticancer agent can cause dose-dependent cardiotoxicity and heart failure
in the long term. Rutin as a polyphenolic flavonoid has been illustrated to protect hearts from …

Danshensu, as the effective component of Salvia miltiorrhiza (Danshen), has been widely
used in clinic for treatment of cardiovascular diseases in China. In the present study, we …

Background Doxorubicin (DOX) is a potent anticancer chemotherapeutic agent whose
clinical application is substantially constrained by its cardiotoxicity. The pathophysiology of …

The flavonoid compound Isorhamnetin (IRMN) is known for its considerable
pharmacological properties, which include antioxidant and anti-inflammatory effects, as well …

Background Doxorubicin is effective in a variety of solid and hematological malignancies.
Unfortunately, clinical application of doxorubicin is limited due to a cumulative dose …

Administration of Chemotherapeutics, especially doxorubicin (DOX) and cyclophosphamide
(CPS), is commonly associated with adverse effects such as myelosuppression and …

Doxorubicin (DOX) is an eff; ective chemotherapeutic drug to suppress the progression of
various types of tumors. However, its clinical application has been largely limited due to its …